Identification of Conserved Proteomic Networks in Neurodegenerative Dementia
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.107807
Abstract: SUMMARY Data-driven analyses are increasingly valued in modern medicine. We integrate quantitative proteomics and transcriptomics from over 1,000 post-mortem brains from six cohorts representing Alzheimer’s disease (AD), asymptomatic AD, progressive supranuclear palsy (PSP), and control… read more here.
Keywords: medicine; proteomic networks; neurodegenerative dementia; conserved proteomic ... See more keywords
Causes of Mortality in Korean Patients with Neurodegenerative Dementia
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DOI: 10.1155/2022/3206594
Abstract: The prevalence of neurodegenerative dementia is increasing owing to the rapid growth of the older population. We investigated risks and causes of mortality in Korean patients with neurodegenerative dementia using data from the Korean Health… read more here.
Keywords: causes mortality; patients neurodegenerative; mortality korean; neurodegenerative dementia ... See more keywords
Brain Perfusion Single-Photon Emission Computed Tomography Using an Easy Z-Score Imaging System Predicts Progression to Neurodegenerative Dementia in Rapid Eye Movement Sleep Behavior Disorder
Sign Up to like & getrecommendations! Published in 2022 at "Dementia and Geriatric Cognitive Disorders"
DOI: 10.1159/000521645
Abstract: Introduction: Longitudinal studies have reported that patients with idiopathic rapid eye movement sleep behavior disorder (IRBD) have an increased risk of developing synucleinopathies, such as Parkinson’s disease and dementia with Lewy bodies (DLB). Clinical trials… read more here.
Keywords: movement sleep; eye movement; dementia; score ... See more keywords
CISD2 Attenuates Inflammation and Regulates Microglia Polarization in EOC Microglial Cells—As a Potential Therapeutic Target for Neurodegenerative Dementia
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2020.00260
Abstract: Background: Accumulating evidence has demonstrated a significant association between microglia-driven inflammation in the brain and neurodegenerative dementia. We previously showed a significant decline in CISD2 expression in mice models with advanced age. Moreover, we observed… read more here.
Keywords: neurodegenerative dementia; eoc microglial; cisd2; inflammation ... See more keywords
Targets and mechanisms of Alpinia oxyphylla Miquel fruits in treating neurodegenerative dementia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.1013891
Abstract: The dried and ripe fruits of Alpinia oxyphylla and ripe fruits of Alpinia oxyphylla Miquel (AO) have the effects of tonifying kidney-essence and nourishing intelligence and thus have been widely used in treating dementia. Alzheimer’s… read more here.
Keywords: alpinia oxyphylla; neurodegenerative dementia; kidney essence; dementia ... See more keywords
Impact of normative brain volume reports on the diagnosis of neurodegenerative dementia disorders in neuroradiology: A real-world, clinical practice study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.971863
Abstract: Background: Normative brain volume reports (NBVR) are becoming more available in the work-up of patients with suspected dementia disorders, potentially leveraging the value of structural MRI in clinical settings. The present study aims to investigate… read more here.
Keywords: world clinical; impact; clinical practice; dementia disorders ... See more keywords