Classification Accuracy of Transcranial Magnetic Stimulation for the Diagnosis of Neurodegenerative Dementias
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DOI: 10.1002/ana.25677
Abstract: Transcranial magnetic stimulation (TMS) has been suggested as a reliable, noninvasive, and inexpensive tool for the diagnosis of neurodegenerative dementias. In this study, we assessed the classification performance of TMS parameters in the differential diagnosis… read more here.
Keywords: diagnosis neurodegenerative; diagnosis; neurodegenerative dementias; transcranial magnetic ... See more keywords
Magnetic Resonance Spectroscopy in neurodegenerative dementias, prodromal syndromes and at-risk states: a systematic review of the literature.
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DOI: 10.1002/nbm.4896
Abstract: BACKGROUND In recent years, magnetic resonance spectroscopy (MRS) has benefited from increased MRI field strengths, new acquisition protocols, and new processing techniques. This review aims to determine how this has altered our understanding of MRS… read more here.
Keywords: magnetic resonance; resonance spectroscopy; review; spectroscopy ... See more keywords
Phytotherapeutic alternatives for neurodegenerative dementias: Scientific review, discussion and therapeutic proposal
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DOI: 10.1002/ptr.7727
Abstract: The incidence and prevalence of age‐related neurodegenerative dementias have been increasing. There is no curative therapy and conventional drug treatment can cause problems for patients. Medicinal plants traditionally used for problems associated with ageing are… read more here.
Keywords: alternatives neurodegenerative; proposal; neurodegenerative dementias; phytotherapeutic alternatives ... See more keywords
Value-Generating Exploratory Trials in Neurodegenerative Dementias
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DOI: 10.1212/wnl.0000000000011774
Abstract: Drug development for Alzheimer disease and other neurodegenerative dementias, including frontotemporal dementia, has experienced a long history of phase 2 and phase 3 clinical trials that failed to show efficacy of investigational drugs. Despite differences… read more here.
Keywords: development; trials neurodegenerative; exploratory trials; value generating ... See more keywords
From clinical phenotype to proteinopathy: molecular neuroimaging in neurodegenerative dementias
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DOI: 10.1590/0004-282x-anp-2022-s138
Abstract: ABSTRACT Neurodegenerative dementias are characterized by the abnormal accumulation of misfolded proteins. However, its diagnostic criteria are still based on the clinical phenotype. The development of biomarkers allowed in vivo detection of pathophysiological processes. This… read more here.
Keywords: proteinopathy; neurodegenerative dementias; clinical phenotype; molecular neuroimaging ... See more keywords