Fluorescent Diagnostic Probes in Neurodegenerative Diseases.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced materials"
DOI: 10.1002/adma.202001945
Abstract: Neurodegenerative diseases are debilitating disorders that feature progressive and selective loss of function or structure of anatomically or physiologically associated neuronal systems. Both chronic and acute neurodegenerative diseases are associated with high morbidity and mortality… read more here.
Keywords: neurodegenerative disease; neurodegenerative diseases; fluorescent diagnostic; probes neurodegenerative ... See more keywords
Caregiving concerns and clinical characteristics across neurodegenerative and cerebrovascular disorders in the Ontario neurodegenerative disease research initiative
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.5727
Abstract: Caregiving burdens are a substantial concern in the clinical care of persons with neurodegenerative disorders. In the Ontario Neurodegenerative Disease Research Initiative, we used the Zarit's Burden Interview (ZBI) to examine: (1) the types of… read more here.
Keywords: ontario neurodegenerative; research initiative; disorders ontario; disease research ... See more keywords
The application of in vitro‐derived human neurons in neurodegenerative disease modeling
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24615
Abstract: The development of safe and effective treatments for age‐associated neurodegenerative disorders is an on‐going challenge faced by the scientific field. Key to the development of such therapies is the appropriate selection of modeling systems in… read more here.
Keywords: neurodegenerative disease; disease; application; application vitro ... See more keywords
Targeted copy number variant identification across the neurodegenerative disease spectrum
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1986
Abstract: Although genetic factors are known to contribute to neurodegenerative disease susceptibility, there remains a large amount of heritability unaccounted for across the diagnoses. Copy number variants (CNVs) contribute to these phenotypes, but their presence and… read more here.
Keywords: number variant; disease; targeted copy; copy number ... See more keywords
Perinatal diesel exhaust exposure causes persistent changes in the brains of aged mice: An assessment of behavioral and biochemical endpoints related to neurodegenerative disease
Sign Up to like & getrecommendations! Published in 2023 at "Environmental Toxicology"
DOI: 10.1002/tox.23733
Abstract: Epidemiological studies support an association between air pollution exposure, specifically particulate matter (PM), and neurodegenerative disease. Diesel exhaust (DE) is a principal component of ambient air pollution and a major contributor of PM. Our study… read more here.
Keywords: diesel exhaust; disease; biochemical endpoints; neurodegenerative disease ... See more keywords
Integrated neurodegenerative disease autopsy diagnosis
Sign Up to like & getrecommendations! Published in 2018 at "Acta Neuropathologica"
DOI: 10.1007/s00401-018-1827-x
Abstract: The classification of human neurodegenerative diseases, while heavily dependent on neuropathologic analyses, increasingly relies on a number of data sources. Advances in the classification of clinical phenotypes and the expansion of molecular genetic alterations associated… read more here.
Keywords: neurodegenerative disease; integrated neurodegenerative; disease; autopsy diagnosis ... See more keywords
AAA+ Protein-Based Technologies to Counter Neurodegenerative Disease.
Sign Up to like & getrecommendations! Published in 2019 at "Biophysical journal"
DOI: 10.1016/j.bpj.2019.03.007
Abstract: Protein misfolding and overloaded proteostasis networks underlie a range of neurodegenerative diseases. No cures exist for these diseases, but developing effective therapeutic agents targeting the toxic, misfolded protein species in disease is one promising strategy. AAA+… read more here.
Keywords: protein; protein misfolding; neurodegenerative disease; aaa protein ... See more keywords
Multidimensional apathy: evidence from neurodegenerative disease
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Behavioral Sciences"
DOI: 10.1016/j.cobeha.2017.12.022
Abstract: Apathy is a demotivation syndrome common in neurodegenerative diseases and is fundamentally multidimensional in nature. Different methodologies have been used to identify and quantify these dimensions, which has resulted in multifarious concepts, ranging in the… read more here.
Keywords: multidimensional apathy; neurodegenerative disease; apathy evidence; disease ... See more keywords
Mesenchymal stromal cells (MSCs) for neurodegenerative disease: A promising frontier.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of cell biology"
DOI: 10.1016/j.ejcb.2020.151097
Abstract: Neurodegenerative disorders are a variety of diseases including Alzheimer's (AD), Parkinson's (PD), and Huntington's diseases (HD), multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS) along with some other less common diseases generally described by the… read more here.
Keywords: neurodegenerative disease; mesenchymal stromal; mscs neurodegenerative; stromal cells ... See more keywords
Development of a reliable microRNA based electrochemical genosensor for monitoring of miR-146a, as key regulatory agent of neurodegenerative disease.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.05.061
Abstract: A MicroRNA (miR) based electrochemical method for quantification of miR-146a, a known biomarker for neurodegenerative disease, was developed. In this bioassay, the capture microRNA (C-miR) was self-assembled on the gold surface and used for quantification… read more here.
Keywords: neurodegenerative disease; mir 146a; mir; microrna based ... See more keywords
Corrigendum to “Spontaneous narrative production in focal neurodegenerative disease” [Neuropsychologia 97 (2015) 158–171]
Sign Up to like & getrecommendations! Published in 2018 at "Neuropsychologia"
DOI: 10.1016/j.neuropsychologia.2017.12.026
Abstract: The authors regret that there was an error in the initial given for Guido F. Schauer in the author list of the original publication. This is now corrected here. The authors and publisher would like… read more here.
Keywords: corrigendum spontaneous; neurodegenerative disease; production focal; spontaneous narrative ... See more keywords