Cognitive resistance to and resilience against multiple comorbid neurodegenerative pathologies and the impact of APOE status.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlac115
Abstract: Alzheimer disease (AD) is currently the leading cause of cognitive decline and dementia worldwide. Recently, studies have suggested that other neurodegenerative comorbidities such as limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC), Lewy body disease (LBD),… read more here.
Keywords: cognitive resistance; disease; neurodegenerative pathologies; resistance resilience ... See more keywords
Thermodynamic Signatures of Blood Plasma Proteome in Neurodegenerative Pathologies
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010789
Abstract: Discovery of diagnostic biomarkers for age-related neurodegenerative pathologies (NDDs) is essential for accurate diagnosis, following disease progression and drug development. Blood plasma and blood cells are important peripheral sources for NDDs’ biomarkers that, although present… read more here.
Keywords: thermodynamic signatures; signatures blood; plasma proteome; neurodegenerative pathologies ... See more keywords