Toward Precision Medicine In Neurodevelopmental Diseases
Sign Up to like & getrecommendations! Published in 2017 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2016.09.375
Abstract: Abstract One primary challenge in the interpretation of large-scale sequencing studies is the huge number of candidate variants that emerge. This occurs primarily because there are many functional variants in every sequenced genome and because… read more here.
Keywords: medicine; precision medicine; medicine neurodevelopmental; toward precision ... See more keywords
The link of organophosphorus pesticides with neurodegenerative and neurodevelopmental diseases based on evidence and mechanisms.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology"
DOI: 10.1016/j.tox.2018.07.014
Abstract: Organophosphorus (OP) compounds have been known as the most widely used pesticides during the past half century and there have been a huge body of literature regarding their association with human chronic diseases. Neurodegenerative and… read more here.
Keywords: link organophosphorus; neurodegenerative neurodevelopmental; organophosphorus pesticides; evidence ... See more keywords
Recent developments in muscle synergy analysis in young people with neurodevelopmental diseases: A Systematic Review
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1145937
Abstract: The central nervous system simplifies motor control by sending motor commands activating groups of muscles, known as synergies. Physiological locomotion can be described as a coordinated recruitment of four to five muscle synergies. The first… read more here.
Keywords: neurodevelopmental diseases; synergy analysis; muscle synergies; muscle ... See more keywords
Neurodegenerative and Neurodevelopmental Diseases and the Gut-Brain Axis: The Potential of Therapeutic Targeting of the Microbiome
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24119577
Abstract: The human gut microbiome contains the largest number of bacteria in the body and has the potential to greatly influence metabolism, not only locally but also systemically. There is an established link between a healthy,… read more here.
Keywords: neurodevelopmental diseases; brain; gut brain; neurodegenerative neurodevelopmental ... See more keywords
Selenium Status in Paediatric Patients with Neurodevelopmental Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14122375
Abstract: Neurodevelopmental diseases are often associated with other comorbidities, especially inflammatory processes. The disease may affect the trace element (TE) status, which in turn may affect disease severity and progression. Selenium (Se) is an essential TE… read more here.
Keywords: neurodevelopmental diseases; paediatric patients; gpx3 activity; status ... See more keywords
Synaptic alterations as a common phase in neurological and neurodevelopmental diseases: JNK is a key mediator in synaptic changes
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.346488
Abstract: Brain synapses play a key role in neuronal communication: this “conversation” is at the basis of all brain activities and synaptic dysfunction leads to brain disorders. We study the modulators of this crucial synaptic function… read more here.
Keywords: common phase; neurodevelopmental diseases; synaptic alterations; alterations common ... See more keywords