Association of Antidepressant Use During Pregnancy With Risk of Neurodevelopmental Disorders in Children.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2022.4268
Abstract: Importance Antidepressant use during pregnancy has been associated with neurodevelopmental disorders in children in some studies. However, results may be explained by uncontrolled confounding by parental mental health status, genetics, and environmental factors. Objective To… read more here.
Keywords: neurodevelopmental disorders; disorders children; antidepressant; antidepressant use ... See more keywords
Neurodevelopmental Disorders in Offspring Conceived via In Vitro Fertilization vs Intracytoplasmic Sperm Injection
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.48141
Abstract: This cohort study assesses the incidence of neurodevelopment disorders, including autism spectrum disorder, attention-deficit/hyperactivity disorder, and developmental delay, in offspring of individuals who received assisted reproductive technology. read more here.
Keywords: neurodevelopmental disorders; via vitro; conceived via; vitro fertilization ... See more keywords
Diagnostic Yield and Novel Candidate Genes by Exome Sequencing in 152 Consanguineous Families With Neurodevelopmental Disorders
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Psychiatry"
DOI: 10.1001/jamapsychiatry.2016.3798
Abstract: Importance Autosomal recessive inherited neurodevelopmental disorders are highly heterogeneous, and many, possibly most, of the disease genes are still unknown. Objectives To promote the identification of disease genes through confirmation of previously described genes and… read more here.
Keywords: exome sequencing; 152 consanguineous; diagnostic yield; consanguineous families ... See more keywords
Neurodevelopmental Disorders Among Publicly or Privately Insured Children in the United States.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2021.3815
Abstract: Importance Neurodevelopmental disorders are associated with poor health and social outcomes. Population-based data on incidence, age at diagnosis, and demographic variations are essential to identify modifiable risk factors and inform the planning of services and… read more here.
Keywords: neurodevelopmental disorders; insured children; incidence; diagnosis ... See more keywords
A recurrent PJA1 variant in trigonocephaly and neurodevelopmental disorders
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51093
Abstract: Neurodevelopmental disorders (NDDs) often associate with epilepsy or craniofacial malformations. Recent large‐scale DNA analyses identified hundreds of candidate genes for NDDs, but a large portion of the cases still remain unexplained. We aimed to identify… read more here.
Keywords: recurrent pja1; neurology; variant trigonocephaly; trigonocephaly neurodevelopmental ... See more keywords
Comprehensive Behavioral Phenotyping of a 16p11.2 Del Mouse Model for Neurodevelopmental Disorders
Sign Up to like & getrecommendations! Published in 2020 at "Autism Research"
DOI: 10.1002/aur.2357
Abstract: The microdeletion of copy number variant 16p11.2 is one of the most common genetic mutations associated with neurodevelopmental disorders, such as Autism Spectrum Disorders (ASDs). Here, we describe our comprehensive behavioral phenotyping of the 16p11.2… read more here.
Keywords: phenotyping 16p11; behavioral phenotyping; delm males; neurodevelopmental disorders ... See more keywords
Cerebellar gamma‐aminobutyric acid: Investigation of group effects in neurodevelopmental disorders
Sign Up to like & getrecommendations! Published in 2023 at "Autism Research"
DOI: 10.1002/aur.2888
Abstract: Neurodevelopmental disorders (NDDs) including autism spectrum disorder (ASD), attention‐deficit hyperactivity disorder (ADHD) and obsessive–compulsive disorder (OCD) are thought to arise in part from the disruption in the excitatory/inhibitory balance of gamma‐aminobutyric acid (GABA) and glutamate… read more here.
Keywords: gamma aminobutyric; neurodevelopmental disorders; aminobutyric acid; group effects ... See more keywords
A systematic review of randomized controlled trials on efficacy and safety of transcranial direct current stimulation in major neurodevelopmental disorders: ADHD, autism, and dyslexia
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2724
Abstract: Among the target groups in child and adolescent psychiatry, transcranial direct current stimulation (tDCS) has been more applied in neurodevelopmental disorders specifically, attention‐deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and dyslexia. This systematic review… read more here.
Keywords: neurodevelopmental disorders; transcranial direct; direct current; systematic review ... See more keywords
Recurrent reciprocal copy number variants: Roles and rules in neurodevelopmental disorders
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22587
Abstract: Deletions and duplications, called reciprocal CNVs when they occur at the same locus, are implicated in neurodevelopmental phenotypes ranging from morphological to behavioral. In this article, we propose three models of how differences in gene… read more here.
Keywords: copy number; variants roles; reciprocal copy; number variants ... See more keywords
Polycomb‐mediated gene regulation in human brain development and neurodevelopmental disorders
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22876
Abstract: The neocortex is considered the seat of higher cognitive function in humans. It develops from a sheet of neural progenitor cells, most of which eventually give rise to neurons. This process of cell fate determination… read more here.
Keywords: neurodevelopmental disorders; pcg; development; regulation human ... See more keywords
Chromosomal microarray in postnatal diagnosis of congenital anomalies and neurodevelopmental disorders in Serbian patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24441
Abstract: Array‐based genomic analysis is a gold standard for the detection of copy number variations (CNVs) as an important source of benign as well as pathogenic variations in humans. The introduction of chromosomal microarray (CMA) has… read more here.
Keywords: neurodevelopmental disorders; microarray postnatal; postnatal diagnosis; chromosomal microarray ... See more keywords