Technical Considerations in Stereotactic Ablative Radiotherapy for Localized Neuroendocrine Cancer of the Lung: Case Report and Review of the Literature
Sign Up to like & getrecommendations! Published in 2019 at "Advances in Radiation Oncology"
DOI: 10.1016/j.adro.2018.10.002
Abstract: Abstract Stereotactic ablative radiotherapy as a treatment option for stage I neuroendocrine cancer of the lung is not yet well understood. While analogs can be made to non-small cell lung cancer, high-grade neuroendocrine tumors are… read more here.
Keywords: neuroendocrine cancer; cancer lung; ablative radiotherapy; cancer ... See more keywords
USP7 inhibitors, downregulating CCDC6, sensitize lung neuroendocrine cancer cells to PARP-inhibitor drugs.
Sign Up to like & getrecommendations! Published in 2017 at "Lung cancer"
DOI: 10.1016/j.lungcan.2016.06.015
Abstract: OBJECTIVES CCDC6 gene product is a tumor-suppressor pro-apoptotic protein, substrate of ATM, involved in DNA damage response and repair. Altered levels of CCDC6 expression are dependent on post-translational modifications, being the de-ubiquitinating enzyme USP7 responsible… read more here.
Keywords: neuroendocrine cancer; cells parp; cancer cells; cancer ... See more keywords