Novel staging for gastric neuroendocrine neoplasms by incorporating the WHO grading into the TNM staging system
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DOI: 10.1002/cam4.5437
Abstract: The 8th tumor‐node‐metastasis (TNM) classification of the American Joint Committee on Cancer (AJCC) can be used to estimate the prognosis of gastric neuroendocrine tumor (gNET) and gastric neuroendocrine carcinoma (gNEC) patients but not gastric neuroendocrine… read more here.
Keywords: novel staging; staging gastric; gastric neuroendocrine; neoplasms incorporating ... See more keywords
New frontiers in imaging including radiomics updates for pancreatic neuroendocrine neoplasms
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DOI: 10.1007/s00261-020-02833-8
Abstract: To illustrate the applications of various imaging tools including conventional MDCT, MRI including DWI, CT & MRI radiomics, FDG & DOTATATE PET-CT for diagnosis, staging, grading, prognostication, treatment planning and assessing treatment response in cases… read more here.
Keywords: pancreatic neuroendocrine; prognosis; treatment; neuroendocrine neoplasms ... See more keywords
Rectal neuroendocrine neoplasms: what the radiologists should know
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DOI: 10.1007/s00261-022-03474-9
Abstract: Neuroendocrine neoplasms of the rectum (R-NENs) are rare; however, their incidence has increased almost threefold in the last few decades. Imaging of R-NENs includes two primary categories: anatomic/morphologic imaging comprised of endoscopic ultrasound (EUS), computed… read more here.
Keywords: radiology; tomography; neuroendocrine neoplasms; neoplasms radiologists ... See more keywords
Preoperative Imaging Overestimates the Tumor Size in Pancreatic Neuroendocrine Neoplasms Associated with Multiple Endocrine Neoplasia Type 1
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DOI: 10.1007/s00268-017-4317-8
Abstract: BackgroundRadiological tumor size of non-functioning pancreatic neuroendocrine neoplasms (Nf-pNENs) associated with multiple endocrine neoplasia type 1 (MEN1) is a crucial parameter to indicate surgery. The aim of this study was to compare radiological size (RS)… read more here.
Keywords: tumor size; pancreatic neuroendocrine; associated multiple; neuroendocrine neoplasms ... See more keywords
Can We Do Even Better? Preoperative Imaging Overestimates the Tumor Size in Pancreatic Neuroendocrine Neoplasms Associated with Multiple Endocrine Neoplasia Type 1
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DOI: 10.1007/s00268-017-4376-x
Abstract: Dr. Polenta and her colleagues have provided our neuroendocrine surgical community with a very interesting and detailed assessment of the accuracy of preoperative imaging for pancreatic neuroendocrine neoplasms (pNEN) in patients with multiple endocrine neoplasia… read more here.
Keywords: multiple endocrine; pancreatic neuroendocrine; neuroendocrine neoplasms; endocrine neoplasia ... See more keywords
Chemoprevention with Somatuline© Delays the Progression of Pancreatic Neuroendocrine Neoplasms in a Mouse Model of Multiple Endocrine Neoplasia Type 1 (MEN1)
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DOI: 10.1007/s00268-018-4839-8
Abstract: ObjectiveLong-acting synthetic somatostatin analogues (SSA) are an essential part of the treatment of neuroendocrine neoplasms. We evaluated the chemopreventive effects of a long-acting somatostatin analogue on the development of pancreatic neuroendocrine neoplasms (pNENs) in a… read more here.
Keywords: pancreatic neuroendocrine; neuroendocrine neoplasms; group; men1 ... See more keywords
Prognostic Factors in Curative Resected Locoregional Small Intestine Neuroendocrine Neoplasms
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DOI: 10.1007/s00268-020-05884-6
Abstract: Small intestinal neuroendocrine neoplasms (SI-NEN) are rare, and only about 40% of patients are diagnosed without distant metastases. Aim of the study was to identify prognostic factors in patients with potentially curative resected locoregional SI-NEN.… read more here.
Keywords: recurrence; curative resected; prognostic factors; neuroendocrine neoplasms ... See more keywords
An update on the development of concepts, diagnostic criteria, and challenging issues for neuroendocrine neoplasms across different digestive organs
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DOI: 10.1007/s00428-022-03306-7
Abstract: Digestive neuroendocrine neoplasms (NENs) are a group of heterogeneous neoplasms found throughout the digestive tract, with different behaviour and genetic background. In the last few years, nomenclature and WHO/UICC classifications of digestive NENs have changed,… read more here.
Keywords: concepts diagnostic; diagnostic criteria; neuroendocrine neoplasms; criteria challenging ... See more keywords
Advanced Pancreatic Neuroendocrine Neoplasms: Which Systemic Treatment Should I Start With?
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DOI: 10.1007/s11912-021-01071-5
Abstract: Pancreatic neuroendocrine neoplasms (panNENs) often present as advanced disease and there is little data to guide treatment sequencing in the advance disease setting. Therefore, we aim to provide a comprehensive summary of the current evidence… read more here.
Keywords: systemic treatment; pancreatic neuroendocrine; treatment; neuroendocrine neoplasms ... See more keywords
What Is the Status of Immunotherapy in Neuroendocrine Neoplasms?
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DOI: 10.1007/s11912-022-01235-x
Abstract: Immunotherapy has changed the treatment of patients with advanced cancer, with different phase III trials showing durable responses across different histologies. This review focuses on the preclinical and clinical evidence of potential predictive biomarkers of… read more here.
Keywords: status immunotherapy; immunotherapy neuroendocrine; oncology; neuroendocrine neoplasms ... See more keywords
Cyclin-dependent Kinases 4/6 Inhibitors in Neuroendocrine Neoplasms: from Bench to Bedside
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DOI: 10.1007/s11912-022-01251-x
Abstract: Cyclin-dependent kinases (CDKs) are key regulators that play an important role in cell division. Palbociclib, ribociclib and abemaciclib showed significant antitumor activity in several malignancies and, recently, also a myeloprotective effect for trilaciclib when added… read more here.
Keywords: neuroendocrine neoplasms; dependent kinases; cdk4 inhibitors; inhibitors neuroendocrine ... See more keywords