Association of Cerebrospinal Fluid Neurofilament Heavy Protein Levels With Clinical Progression in Patients With Parkinson Disease
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.23821
Abstract: Key Points Question Are cerebrospinal fluid (CSF) neurofilament heavy (cNfH) levels associated with clinical progression in patients with Parkinson disease? Findings In this cohort study of 404 patients with Parkinson disease, higher baseline cNfH levels… read more here.
Keywords: patients parkinson; progression; parkinson disease; cerebrospinal fluid ... See more keywords
Neurofilament Heavy Chain and Tau Protein Are Not Elevated in Cerebrospinal Fluid of Adult Patients with Spinal Muscular Atrophy during Loading with Nusinersen
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DOI: 10.3390/ijms20215397
Abstract: Nusinersen is the first approved drug for the treatment of spinal muscular atrophy (SMA). Treatment of SMA with nusinersen is based on a fixed dosing regimen. For other motoneuron diseases, such as amyotrophic lateral sclerosis… read more here.
Keywords: neurofilament heavy; chain tau; heavy chain; tau protein ... See more keywords
Phosphorylated neurofilament heavy: A potential blood biomarker to evaluate the severity of acute spinal cord injuries in adults
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Critical Illness and Injury Science"
DOI: 10.4103/ijciis.ijciis_73_16
Abstract: Aims: The aim of this study is to analyze the serial estimation of phosphorylated neurofilament heavy (pNF-H) in blood plasma that would act as a potential biomarker for early prediction of the neurological severity of… read more here.
Keywords: biomarker; pnf; correlation; severity ... See more keywords