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   Articles with "neurogenic detrusor" as a keyword



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Efficacy and safety of mirabegron for the treatment of neurogenic detrusor overactivity—Prospective, randomized, double‐blind, placebo‐controlled study

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recommendations! Published in 2018 at "Neurourology and Urodynamics"

DOI: 10.1002/nau.23566

Abstract: To assess the efficacy and safety of mirabegron in the treatment of neurogenic detrusor overactivity. read more here.

Keywords: treatment neurogenic; mirabegron treatment; efficacy safety; neurogenic detrusor ... See more keywords

Effects of early intravesical administration of resiniferatoxin to spinal cord‐injured rats in neurogenic detrusor overactivity

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recommendations! Published in 2019 at "Neurourology and Urodynamics"

DOI: 10.1002/nau.24032

Abstract: To investigate if intravesical administration during spinal shock of resiniferatoxin (RTX), an ultrapotent desensitizing agonist of transient receptor potential vanilloid‐1 (TRPV1), would silence TRPV1‐expressing bladder afferents at an early stage of disease progression and modulate… read more here.

Keywords: neurogenic detrusor; intravesical administration; detrusor overactivity; resiniferatoxin ... See more keywords

Efficacy and safety of mirabegron in children and adolescents with neurogenic detrusor overactivity: An open‐label, phase 3, dose‐titration study

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recommendations! Published in 2021 at "Neurourology and Urodynamics"

DOI: 10.1002/nau.24657

Abstract: To evaluate the efficacy and safety of mirabegron in children and adolescents (aged 3 to read more here.

Keywords: efficacy safety; neurogenic detrusor; safety mirabegron; children adolescents ... See more keywords
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Intravesical oxybutynin therapy for patients with neurogenic detrusor overactivity: a systematic review and meta-analysis

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recommendations! Published in 2022 at "International Urology and Nephrology"

DOI: 10.1007/s11255-022-03129-0

Abstract: To evaluate the effectiveness and safety of intravesical oxybutynin therapy for patients with neurogenic detrusor overactivity. A systematic search in PubMed, MEDLINE, EMBASE, ClinicalTrial.gov, and Cochrane Controlled Trials Register was conducted from 1990 to 2021.… read more here.

Keywords: oxybutynin; intravesical oxybutynin; detrusor overactivity; neurogenic detrusor ... See more keywords

Clinical and Urodynamic Results of Repeated Intradetrusor Onabotulinum Toxin A Injections in Refractory Neurogenic Detrusor Overactivity: Up to 5 Injections in a Cohort of Children With Myelodysplasia.

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recommendations! Published in 2018 at "Urology"

DOI: 10.1016/j.urology.2017.09.005

Abstract: OBJECTIVE To determine the efficacy and safety of repeated intradetrusor onabotulinum toxin A (onaBoNT-A) injections in children with neurogenic detrusor overactivity due to myelodysplasia. MATERIALS AND METHODS The study group consisted of 19 children (4… read more here.

Keywords: detrusor; neurogenic detrusor; intradetrusor onabotulinum; repeated intradetrusor ... See more keywords
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Efficacy of abobotulinumtoxinA versus onabotulinumtoxinA for the treatment of refractory neurogenic detrusor overactivity: a systematic review and indirect treatment comparison.

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recommendations! Published in 2023 at "Journal of medical economics"

DOI: 10.1080/13696998.2023.2165366

Abstract: AIMS To compare the efficacy and safety of abobotulinumtoxinA1 (aboBoNT-A) and onabotulinumtoxinA2 (onaBoNT-A) for the treatment of refractory neurogenic detrusor overactivity (NDO), using indirect treatment comparison (ITC). MATERIALS AND METHODS A systematic literature review was… read more here.

Keywords: neurogenic detrusor; treatment refractory; detrusor overactivity; refractory neurogenic ... See more keywords

Positive outcomes with first onabotulinumtoxinA treatment persist in the long term with repeat treatments in patients with neurogenic detrusor overactivity

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recommendations! Published in 2017 at "BJU International"

DOI: 10.1111/bju.13795

Abstract: To examine whether response to first treatment with onabotulinumtoxinA is predictive of long‐term treatment outcome in patients with neurogenic detrusor overactivity (NDO). read more here.

Keywords: neurogenic detrusor; long term; treatment; detrusor overactivity ... See more keywords

Adaptive changes of telocytes in the urinary bladder of patients affected by neurogenic detrusor overactivity

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recommendations! Published in 2018 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.13308

Abstract: Urinary bladder activity involves central and autonomic nervous systems and bladder wall. Studies on the pathogenesis of voiding disorders such as the neurogenic detrusor overactivity (NDO) due to suprasacral spinal cord lesions have emphasized the… read more here.

Keywords: detrusor; neurogenic detrusor; bladder; urinary bladder ... See more keywords

TASCI—transcutaneous tibial nerve stimulation in patients with acute spinal cord injury to prevent neurogenic detrusor overactivity: protocol for a nationwide, randomised, sham-controlled, double-blind clinical trial

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recommendations! Published in 2020 at "BMJ Open"

DOI: 10.1136/bmjopen-2020-039164

Abstract: Introduction Neurogenic lower urinary tract dysfunction (NLUTD), including neurogenic detrusor overactivity (NDO) and detrusor sphincter dyssynergia, is one of the most frequent and devastating sequelae of spinal cord injury (SCI), as it can lead to… read more here.

Keywords: ttns; trial; detrusor; neurogenic detrusor ... See more keywords

Molecular Mechanism Operating in Animal Models of Neurogenic Detrusor Overactivity: A Systematic Review Focusing on Bladder Dysfunction of Neurogenic Origin

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recommendations! Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24043273

Abstract: Neurogenic detrusor overactivity (NDO) is a severe lower urinary tract disorder, characterized by urinary urgency, retention, and incontinence, as a result of a neurologic lesion that results in damage in neuronal pathways controlling micturition. The… read more here.

Keywords: neurogenic detrusor; detrusor overactivity; dysfunction; animal models ... See more keywords
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BoNT/A1 Secondary Failure for the Treatment of Neurogenic Detrusor Overactivity: An Ex Vivo Functional Study

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recommendations! Published in 2022 at "Toxins"

DOI: 10.3390/toxins14020077

Abstract: Management of neurogenic detrusor overactivity (NDO) remains a clinical priority to improve patients’ quality of life and prevent dramatic urological complications. Intradetrusor injection of onabotulinumtoxinA (BoNT/A1, botulinum neurotoxin A1) is approved as second therapeutic line… read more here.

Keywords: bont secondary; neurogenic detrusor; secondary failure; failure ... See more keywords