Natural α,β-unsaturated lactones inhibit neuropeptide-induced mast cell activation in an in vitro model of neurogenic inflammation
Sign Up to like & getrecommendations! Published in 2020 at "Inflammation Research"
DOI: 10.1007/s00011-020-01380-8
Abstract: Mast cells are involved in not only inducing, but also maintaining neurogenic inflammation and neuropathic pain. In previous work, we have demonstrated that dehydroleucodine, xanthatin and 3-benzyloxymethyl-5H-furan-2-one inhibit rat peritoneal and human LAD2 mast cell… read more here.
Keywords: mast; dehydroleucodine xanthatin; neurogenic inflammation; mast cell ... See more keywords
Neurogenic inflammation in fibromyalgia
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in Immunopathology"
DOI: 10.1007/s00281-018-0672-2
Abstract: Fibromyalgia is a high impact chronic pain disorder with a well-defined and robust clinical phenotype. Key features include widespread pain and tenderness, high levels of sleep disturbance, fatigue, cognitive dysfunction and emotional distress. Abnormal processing… read more here.
Keywords: inflammation fibromyalgia; neurogenic inflammation; fibromyalgia; pain ... See more keywords
Roles of inflammation, neurogenic inflammation, and neuroinflammation in pain
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Anesthesia"
DOI: 10.1007/s00540-018-2579-4
Abstract: Inflammation is the body’s response to injury and infection, involving a complex biological response of the somatosensory, immune, autonomic, and vascular systems. Inflammatory mediators such as prostaglandin, proinflammatory cytokines, and chemokines induce pain via direct… read more here.
Keywords: neurogenic inflammation; roles inflammation; neuroinflammation; inflammation ... See more keywords
Excimer light effect on neurogenic inflammation in active versus stable psoriasis lesions
Sign Up to like & getrecommendations! Published in 2024 at "Lasers in Medical Science"
DOI: 10.1007/s10103-024-04005-2
Abstract: Neurogenic inflammation, mediated by T helper 17 cell (Th17) and neurons that release neuropeptides such as substance P (SP), is thought to play a role in the pathogenesis of psoriasis. Excimer light is used in… read more here.
Keywords: effect; neurogenic inflammation; active versus; excimer light ... See more keywords
The two-faced effects of nerves and neuropeptides in corneal diseases
Sign Up to like & getrecommendations! Published in 2021 at "Progress in retinal and eye research"
DOI: 10.1016/j.preteyeres.2021.100974
Abstract: Corneal nerves are instrumental to maintain cornea integrity through regulation of key physiological functions such as tear secretion, blink reflex, and neuropeptide turnover. Corneal nerve injury/stimulation can follow many insults including mechanical/chemical trauma, infections and… read more here.
Keywords: neurogenic inflammation; two faced; corneal; faced effects ... See more keywords
Sensory ASIC3 channel exacerbates psoriatic inflammation via a neurogenic pathway in female mice
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-49577-3
Abstract: Psoriasis is an immune-mediated skin disease associated with neurogenic inflammation, but the underlying molecular mechanism remains unclear. We demonstrate here that acid-sensing ion channel 3 (ASIC3) exacerbates psoriatic inflammation through a sensory neurogenic pathway. Global… read more here.
Keywords: mice; neurogenic pathway; neurogenic inflammation; exacerbates psoriatic ... See more keywords
Vessel-wall MRI in primary headaches: The role of neurogenic inflammation.
Sign Up to like & getrecommendations! Published in 2022 at "Headache"
DOI: 10.1111/head.14253
Abstract: OBJECTIVE The purpose of this study was to investigate if vessel-wall magnetic resonance imaging (VW-MRI) could differentiate among primary headaches disorders, such as migraine and cluster headache (CH), and detect the presence of neurogenic inflammation.… read more here.
Keywords: neurogenic inflammation; primary headaches; inflammation; vessel wall ... See more keywords
Ultrasonographic assessment of skeletal muscles after experimentally induced neurogenic inflammation (facet injury) in rats
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Biology and Medicine"
DOI: 10.1177/15353702221119802
Abstract: This study set out to examine ultrasonographic attributes of non-neurosegmentally (pectoral-forelimb) and neurosegmentally linked (hindlimb) myotomes in an experimental model that leads to neurogenic inflammation in segmentally linked myotomes, and to evaluate quantitative correlations among… read more here.
Keywords: inflammatory mediators; neurogenic inflammation; ultrasonographic assessment; skeletal muscles ... See more keywords
Neuropeptides SP and CGRP Underlie the Electrical Properties of Acupoints
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2018.00907
Abstract: Electrical skin measurements at acupuncture points (acupoints) have been utilized as a diagnostic and therapeutic aid for more than 50 years. Although acupoints are described as having distinct electrical properties, such as high conductance and… read more here.
Keywords: high conductance; neurogenic inflammation; cgrp; conductance ... See more keywords