Differential vulnerability of adult neurogenic niches to dosage of the neurodevelopmental-disorder linked gene Foxg1
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DOI: 10.1038/s41380-022-01497-8
Abstract: The transcription factor FOXG1 serves pleiotropic functions in brain development ranging from the regulation of precursor proliferation to the control of cortical circuit formation. Loss-of-function mutations and duplications of FOXG1 are associated with neurodevelopmental disorders… read more here.
Keywords: adult neurogenic; foxg1 dosage; differential vulnerability; neurogenic niches ... See more keywords
Extracellular Vesicles, Influential Players of Intercellular Communication within Adult Neurogenic Niches
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DOI: 10.3390/ijms21228819
Abstract: Adult neurogenesis, involving the generation of functional neurons from adult neural stem cells (NSCs), occurs constitutively in discrete brain regions such as hippocampus, sub-ventricular zone (SVZ) and hypothalamus. The intrinsic structural plasticity of the neurogenic… read more here.
Keywords: extracellular vesicles; adult; communication; adult neurogenic ... See more keywords
Effects of β-amyloid (1-42) Administration on the Main Neurogenic Niches of the Adult Brain: Amyloid-Induced Neurodegeneration Influences Neurogenesis
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DOI: 10.3390/ijms232315444
Abstract: Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder and warrants further study as well as timely treatment. Additionally, the mechanisms of the brain’s intrinsic defense against chronic injury are not yet fully understood. Herein,… read more here.
Keywords: vegf sox14; neurogenic niches; positive cells; brain ... See more keywords
Localization and Characterization of Major Neurogenic Niches in the Brain of the Lesser-Spotted Dogfish Scyliorhinus canicula
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DOI: 10.3390/ijms24043650
Abstract: Adult neurogenesis is defined as the ability of specialized cells in the postnatal brain to produce new functional neurons and to integrate them into the already-established neuronal network. This phenomenon is common in all vertebrates… read more here.
Keywords: dogfish scyliorhinus; lesser spotted; neurogenic niches; brain ... See more keywords