AVE 0991 Suppresses Astrocyte-Mediated Neuroinflammation of Alzheimer’s Disease by Enhancing Autophagy
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s392599
Abstract: Purpose Our previous study has shown that AVE 0991, a nonpeptide analogue of Ang-(1-7), ameliorates cognitive decline and inhibits NLRP3 inflammasome of astrocytes in Alzheimer’s disease model mice. Additionally, several studies have suggested that activation… read more here.
Keywords: neuroinflammation alzheimer; alzheimer disease; autophagy; ave 0991 ... See more keywords
A Computational Exploration of the Molecular Network Associated to Neuroinflammation in Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.630003
Abstract: Neuroinflammation, as defined by the presence of classically activated microglia, is thought to play a key role in numerous neurodegenerative disorders such as Alzheimer’s disease. While modulating neuroinflammation could prove beneficial against neurodegeneration, identifying its… read more here.
Keywords: alzheimer disease; associated neuroinflammation; neuroinflammation alzheimer; disease ... See more keywords
Cellular and Molecular Mediators of Neuroinflammation in Alzheimer Disease
Sign Up to like & getrecommendations! Published in 2019 at "International Neurourology Journal"
DOI: 10.5213/inj.1938184.092
Abstract: Alzheimer disease (AD) is a neurodegenerative disorder characterized by the loss of neuronal cells and the progressive decline of cognitive function. The major pathological culprit of AD is aggregation of amyloid-β (Aβ) and hyperphosphorylation of… read more here.
Keywords: mediators neuroinflammation; neuroinflammation alzheimer; alzheimer disease; molecular mediators ... See more keywords