Adalimumab improves cognitive impairment, exerts neuroprotective effects and attenuates neuroinflammation in an Aβ1-40-injected mouse model of Alzheimer's disease.
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DOI: 10.1016/j.jcyt.2019.04.054
Abstract: The pathogenesis of Alzheimer's disease (AD) is associated with an increased inflammatory response via activated microglia and astrocytes. In the present study, we investigated whether treatment with the anti-tumor necrosis factor alpha (TNF-α) monoclonal antibody… read more here.
Keywords: alzheimer disease; neuroinflammation injected; treatment; adalimumab ... See more keywords