Locus Coeruleus Modulates Neuroinflammation in Parkinsonism and Dementia
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21228630
Abstract: Locus Coeruleus (LC) is the main noradrenergic nucleus of the central nervous system, and its neurons widely innervate the whole brain. LC is severely degenerated both in Alzheimer’s disease (AD) and in Parkinson’s disease (PD),… read more here.
Keywords: neuroinflammation parkinsonism; coeruleus modulates; modulates neuroinflammation; locus coeruleus ... See more keywords
LPS Triggers Acute Neuroinflammation and Parkinsonism Involving NLRP3 Inflammasome Pathway and Mitochondrial CI Dysfunction in the Rat
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24054628
Abstract: Whether neuroinflammation leads to dopaminergic nigrostriatal system neurodegeneration is controversial. We addressed this issue by inducing acute neuroinflammation in the substantia nigra (SN) with a single local administration (5 µg/2 µL saline solution) of lipopolysaccharide… read more here.
Keywords: day; neuroinflammation parkinsonism; triggers acute; neuroinflammation ... See more keywords