Targeting microglia attenuates neuroinflammationârelated neural damage in mice carrying human PLP1 mutations
Sign Up to like & getrecommendations! Published in 2019 at "Glia"
DOI: 10.1002/glia.23539
Abstract: Genetically caused neurological disorders of the central nervous system (CNS) usually result in poor or even fatal clinical outcome and few or no causative treatments are available. Often, these disorders are associated with diseaseâamplifying neuroinflammation,… read more here.
Keywords: plp1; related neural; cns; neuroinflammation related ... See more keywords
Acute postoperative pain exacerbates neuroinflammation and related delirium-like cognitive dysfunction in rats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Anesthesia"
DOI: 10.1007/s00540-019-02635-3
Abstract: The acute neuroinflammatory response to surgery may play a key pathogenic role in postoperative delirium (POD). Here, we investigated the contribution of acute postoperative pain to neuroinflammation and related delirium-like behaviors after surgery in adult… read more here.
Keywords: surgery; neuroinflammation related; postoperative pain; delirium ... See more keywords
The Beneficial Roles of SIRT1 in Neuroinflammation-Related Diseases
Sign Up to like & getrecommendations! Published in 2020 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2020/6782872
Abstract: Sirtuins are the class III of histone deacetylases whose deacetylate of histones is dependent on nicotinamide adenine dinucleotide (NAD+). Among seven sirtuins, SIRT1 plays a critical role in modulating a wide range of physiological processes,… read more here.
Keywords: effects sirt1; related diseases; neuroinflammation; sirt1 neuroinflammation ... See more keywords
Translocator Protein 18-kDa: a promising target to treat neuroinflammation-related degenerative diseases.
Sign Up to like & getrecommendations! Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867329666220415120820
Abstract: In the nervous system, inflammatory responses physiologically occur as defense mechanisms triggered by damaging events. If improperly regulated, neuroinflammation can contribute to the development of chronically activated states of glial cells, with the perpetuation of… read more here.
Keywords: neuroinflammation; translocator protein; promising target; neuroinflammation related ... See more keywords