Immunocompetent hamsters as a model for orthobunyavirus-induced neuroinvasion and neuropathology
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0011355
Abstract: Background Bunyavirus infections, including those caused by Bunyamwera serogroup orthobunyaviruses, represent a significant and yet likely still vastly underappreciated cause of mild to moderate human febrile infections. In severe cases, these infections can also cause… read more here.
Keywords: immunocompetent hamsters; infection; neuropathology; model orthobunyavirus ... See more keywords
Mechanisms of the host immune response and helminth-induced pathology during Trichobilharzia regenti (Schistosomatidae) neuroinvasion in mice
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010302
Abstract: Helminth neuroinfections represent serious medical conditions, but the diversity of the host-parasite interplay within the nervous tissue often remains poorly understood, partially due to the lack of laboratory models. Here, we investigated the neuroinvasion of… read more here.
Keywords: spinal cord; pathology; regenti schistosomatidae; trichobilharzia regenti ... See more keywords
A Journey to the Central Nervous System: Routes of Flaviviral Neuroinvasion in Human Disease
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DOI: 10.3390/v14102096
Abstract: Many arboviruses, including viruses of the Flavivirus genera, are known to cause severe neurological disease in humans, often with long-lasting, debilitating sequalae in surviving patients. These emerging pathogens impact millions of people worldwide, yet still… read more here.
Keywords: disease; central nervous; journey central; nervous system ... See more keywords