Interplay between hevin, SPARC, and MDGAs: modulators of neurexin-neuroligin transsynaptic bridges.
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DOI: 10.1016/j.str.2021.01.003
Abstract: Hevin is secreted by astrocytes and its synaptogenic effects are antagonized by the related protein, SPARC. Hevin stabilizes neurexin-neuroligin transsynaptic bridges in vivo. A third protein, membrane-tethered MDGA, blocks these bridges. Here, we reveal the molecular… read more here.
Keywords: sparc; neuroligin transsynaptic; hevin; transsynaptic bridges ... See more keywords