Rab7 may be a novel therapeutic target for neurologic diseases as a key regulator in autophagy
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24034
Abstract: Macroautophagy is an evolutionally conserved membrane trafficking pathway that delivers intracellular materials to lysosomes for degradation and recycling. Rab7, as a member of the Rab GTPase superfamily, has a unique role in the regulation of… read more here.
Keywords: rab7 may; disease; neurologic diseases; therapeutic target ... See more keywords
Viral Encephalitis and Neurologic Diseases: Focus on Astrocytes.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in molecular medicine"
DOI: 10.1016/j.molmed.2018.09.001
Abstract: Neurotropic RNA virus infections cause a major neurological disease burden. Due to the morbidity and mortality rates of viral encephalitides worldwide, there is a need to develop clinical treatments. Features of the central nervous system… read more here.
Keywords: encephalitis neurologic; diseases focus; neurologic diseases; viral encephalitis ... See more keywords
Congenital human cytomegalovirus infection and neurologic diseases in newborns
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DOI: 10.1097/cm9.0000000000000404
Abstract: Abstract Objective: This review aimed to summarize research progress regarding congenital cytomegalovirus (cCMV) infection-related nervous system diseases and their mechanisms. Data sources: All literature quoted in this review was retrieved from PubMed and Web of… read more here.
Keywords: ccmv infection; infection; cytomegalovirus; neurologic diseases ... See more keywords
Is there still a role for hypothermia in neurocritical care?
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Critical Care"
DOI: 10.1097/mcc.0000000000000398
Abstract: Purpose of review Therapeutic hypothermia (i.e. induced body core temperature ≈ 33–35°C) in neurological patients with cerebrovascular disease and traumatic brain injury is a controversially discussed issue in the literature. In this review, we have… read more here.
Keywords: temperature; hypothermia; therapeutic hypothermia; care still ... See more keywords