Is Alzheimer's disease an infectious neurological disease? A review of the literature
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2728
Abstract: Alzheimer's disease (AD) is a leading cause of dementia around the globe. Its pathogenesis is characterized primarily by the extracellular deposition of amyloid β peptides and intracellular neurofibrillary tangles. Despite the significant investments in neurological… read more here.
Keywords: disease; alzheimer disease; neurological disease; disease review ... See more keywords
Oral and intravenous transmission of α-synuclein fibrils to mice
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neuropathologica"
DOI: 10.1007/s00401-019-02037-5
Abstract: Parkinson’s disease and related disorders are neuropathologically characterized by cellular deposits of misfolded and aggregated α-synuclein in the CNS. Disease-associated α-synuclein adopts a conformation that causes it to form oligomers and fibrils, which have reduced… read more here.
Keywords: synuclein; challenge; oral intravenous; synuclein fibrils ... See more keywords
The misdiagnosis of functional disorders as other neurological conditions
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurology"
DOI: 10.1007/s00415-019-09356-3
Abstract: BackgroundSeveral studies have shown that when patients with functional neurological disorders are followed up, it is rare to find another neurological condition that better explains the initial symptoms in hindsight. No study has examined the… read more here.
Keywords: neurology; better explains; diagnosis; disease ... See more keywords
Therapeutic Effect of Agmatine on Neurological Disease: Focus on Ion Channels and Receptors
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemical Research"
DOI: 10.1007/s11064-018-02712-1
Abstract: The central nervous system (CNS) is the most injury-prone part of the mammalian body. Any acute or chronic, central or peripheral neurological disorder is related to abnormal biochemical and electrical signals in the brain cells.… read more here.
Keywords: ion channels; channels receptors; ion; receptor ... See more keywords
Neurological Implications of COVID-19 Infections
Sign Up to like & getrecommendations! Published in 2020 at "Neurocritical Care"
DOI: 10.1007/s12028-020-00978-4
Abstract: The magnitude of the COVID-19 pandemic will result in substantial neurological disease, whether through direct infection (rare), para-infectious complications (less rare), or critical illness more generally (common). Here, we raise the importance of stringent diagnosis… read more here.
Keywords: implications covid; infection; neurological disease; neurological implications ... See more keywords
TRPV4 Channel in Neurological Disease: from Molecular Mechanisms to Therapeutic Potential
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Neurobiology"
DOI: 10.1007/s12035-024-04518-5
Abstract: Transient Receptor Potential Vanilloid 4 (TRPV4) is a non-selective cation channel with pivotal roles in various physiological processes, including osmosensitivity, mechanosensation, neuronal development, vascular tone regulation, and bone homeostasis in human bodies. Recent studies have… read more here.
Keywords: molecular mechanisms; neurological disease; trpv4; trpv4 channel ... See more keywords
Ankyrins and neurological disease
Sign Up to like & getrecommendations! Published in 2021 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2021.01.002
Abstract: Ankyrins are scaffolding proteins widely expressed throughout the nervous system. Ankyrins recruit diverse membrane proteins, including ion channels and cell adhesion molecules, into specialized subcellular membrane domains. These domains are stabilized by ankyrins interacting with… read more here.
Keywords: ankyrins neurological; disease; neurobiology; membrane ... See more keywords
Coreaction Accelerator Au Nanoparticle-Confined Coordination Polymers with Highly Efficient Electrochemiluminescence for Sensitive Detection of Neurological Disease Biomarkers.
Sign Up to like & getrecommendations! Published in 2025 at "ACS sensors"
DOI: 10.1021/acssensors.5c01053
Abstract: In this study, a highly efficient electrochemiluminescent (ECL) coordination polymer, Au-Zn-DTBA, was synthesized by employing 2,2'-dithiodibenzoic acid (DTBA) as the luminescent ligand and Zn2+ as the metal node as well as Au nanoparticles (AuNPs) as… read more here.
Keywords: detection; sensitive detection; coreaction accelerator; dtba ... See more keywords
Xq22 deletion involving TCEAL1 in a female patient with early-onset neurological disease trait
Sign Up to like & getrecommendations! Published in 2024 at "Human Genome Variation"
DOI: 10.1038/s41439-024-00278-9
Abstract: A 3.5-Mb microdeletion in Xq22 was identified in a female patient with early-onset neurological disease trait (EONDT). The patient exhibited developmental delay but no hypomyelination despite PLP1 involvement in the deletion. However, the clinical features… read more here.
Keywords: patient early; onset neurological; neurological disease; early onset ... See more keywords
Excess Wnt in neurological disease
Sign Up to like & getrecommendations! Published in 2025 at "Biochemical Journal"
DOI: 10.1042/bcj20240265
Abstract: Wnt pathways are critical developmental signaling cascades that are conserved across multicellular life. A clear role for Wnt signaling in proper neural development has been well-established, yet less is known about its sustained expression and… read more here.
Keywords: nervous system; wnt; neurological disease; excess wnt ... See more keywords
Neurological disease caused by flavivirus infections
Sign Up to like & getrecommendations! Published in 2018 at "Microbiology Australia"
DOI: 10.1071/ma18029
Abstract: Tristan Gibbs Department of Microbiology, PathWest Laboratory Medicine WA (LMWA), Queen Elizabeth II (QEII) Medical Centre, Hospital Avenue, Nedlands, WA 6009, Australia School of Medicine, Faculty of Health and Medical Sciences, University of Western Australia,… read more here.
Keywords: medicine; disease caused; 6009 australia; caused flavivirus ... See more keywords