Is Alzheimer's disease an infectious neurological disease? A review of the literature
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2728
Abstract: Alzheimer's disease (AD) is a leading cause of dementia around the globe. Its pathogenesis is characterized primarily by the extracellular deposition of amyloid β peptides and intracellular neurofibrillary tangles. Despite the significant investments in neurological… read more here.
Keywords: disease; alzheimer disease; neurological disease; disease review ... See more keywords
Oral and intravenous transmission of α-synuclein fibrils to mice
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neuropathologica"
DOI: 10.1007/s00401-019-02037-5
Abstract: Parkinson’s disease and related disorders are neuropathologically characterized by cellular deposits of misfolded and aggregated α-synuclein in the CNS. Disease-associated α-synuclein adopts a conformation that causes it to form oligomers and fibrils, which have reduced… read more here.
Keywords: synuclein; challenge; oral intravenous; synuclein fibrils ... See more keywords
The misdiagnosis of functional disorders as other neurological conditions
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurology"
DOI: 10.1007/s00415-019-09356-3
Abstract: BackgroundSeveral studies have shown that when patients with functional neurological disorders are followed up, it is rare to find another neurological condition that better explains the initial symptoms in hindsight. No study has examined the… read more here.
Keywords: neurology; better explains; diagnosis; disease ... See more keywords
Therapeutic Effect of Agmatine on Neurological Disease: Focus on Ion Channels and Receptors
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemical Research"
DOI: 10.1007/s11064-018-02712-1
Abstract: The central nervous system (CNS) is the most injury-prone part of the mammalian body. Any acute or chronic, central or peripheral neurological disorder is related to abnormal biochemical and electrical signals in the brain cells.… read more here.
Keywords: ion channels; channels receptors; ion; receptor ... See more keywords
Neurological Implications of COVID-19 Infections
Sign Up to like & getrecommendations! Published in 2020 at "Neurocritical Care"
DOI: 10.1007/s12028-020-00978-4
Abstract: The magnitude of the COVID-19 pandemic will result in substantial neurological disease, whether through direct infection (rare), para-infectious complications (less rare), or critical illness more generally (common). Here, we raise the importance of stringent diagnosis… read more here.
Keywords: implications covid; infection; neurological disease; neurological implications ... See more keywords
Ankyrins and neurological disease
Sign Up to like & getrecommendations! Published in 2021 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2021.01.002
Abstract: Ankyrins are scaffolding proteins widely expressed throughout the nervous system. Ankyrins recruit diverse membrane proteins, including ion channels and cell adhesion molecules, into specialized subcellular membrane domains. These domains are stabilized by ankyrins interacting with… read more here.
Keywords: ankyrins neurological; disease; neurobiology; membrane ... See more keywords
Neurological disease caused by flavivirus infections
Sign Up to like & getrecommendations! Published in 2018 at "Microbiology Australia"
DOI: 10.1071/ma18029
Abstract: Tristan Gibbs Department of Microbiology, PathWest Laboratory Medicine WA (LMWA), Queen Elizabeth II (QEII) Medical Centre, Hospital Avenue, Nedlands, WA 6009, Australia School of Medicine, Faculty of Health and Medical Sciences, University of Western Australia,… read more here.
Keywords: medicine; disease caused; 6009 australia; caused flavivirus ... See more keywords
Endocannabinoid dysfunction in neurological disease: neuro-ocular DAGLA-related syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Brain"
DOI: 10.1093/brain/awac223
Abstract: Abstract The endocannabinoid system is a highly conserved and ubiquitous signalling pathway with broad-ranging effects. Despite critical pathway functions, gene variants have not previously been conclusively linked to human disease. We identified nine children from… read more here.
Keywords: disease; endocannabinoid dysfunction; dagla; neuro ocular ... See more keywords
Invited Review: From nose to gut – the role of the microbiome in neurological disease
Sign Up to like & getrecommendations! Published in 2019 at "Neuropathology and Applied Neurobiology"
DOI: 10.1111/nan.12520
Abstract: Inflammation and neurodegeneration are key features of many chronic neurological diseases, yet the causative mechanisms underlying these processes are poorly understood. There has been mounting interest in the role of the human microbiome in modulating… read more here.
Keywords: invited review; disease; nose gut; role ... See more keywords
Rituximab in neurological disease: principles, evidence and practice
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DOI: 10.1136/practneurol-2018-001899
Abstract: Rituximab is a widely used B-cell-depleting monoclonal antibody. It is unlicensed for use in neurological disorders and there are no treatment guidelines. However, as a rapidly acting, targeted therapy with growing evidence of efficacy and… read more here.
Keywords: disease principles; rituximab neurological; evidence practice; evidence ... See more keywords
Neurological Disease-Affected Patients, including Multiple Sclerosis, Are Poor Responders to BKPyV, a Human Polyomavirus
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/4864950
Abstract: Multiple sclerosis (MS) is a neurological disease characterized by immune dysregulations. Different viruses may act as MS triggering agents. MS patients respond differently to distinct viruses. The aim of our study is to verify the… read more here.
Keywords: multiple sclerosis; poor responders; neurological disease; responders bkpyv ... See more keywords