Vigilance: the behavioral impact of quantitative monitoring on administration and antagonism of neuromuscular blocking agents
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Monitoring and Computing"
DOI: 10.1007/s10877-021-00729-6
Abstract: The aim of this study was to determine whether use of acceleromyography (1) changes dosing of neuromuscular blocking agents (NMBAs), and (2) increases the time between neostigmine administration and extubation, when compared with subjective assessment… read more here.
Keywords: administration; dose nmba; neuromuscular blocking; blocking agents ... See more keywords
Appropriate Use of Neuromuscular Blocking Agents and Reversal Drugs to Enhance Recovery Following Cardiac Surgery
Sign Up to like & getrecommendations! Published in 2020 at "Current Anesthesiology Reports"
DOI: 10.1007/s40140-020-00394-6
Abstract: Purpose of Review To provide a brief review of the use of neuromuscular blocking agents (NMBA) in cardiac surgery, including strategies for reversal and the effects of residual blockade. Recent Findings While ample evidence exists… read more here.
Keywords: following cardiac; surgery; neuromuscular blocking; cardiac surgery ... See more keywords
Integrating basophil activation tests into evaluation of perioperative anaphylaxis to neuromuscular blocking agents.
Sign Up to like & getrecommendations! Published in 2019 at "British journal of anaesthesia"
DOI: 10.1016/j.bja.2019.02.024
Abstract: BACKGROUND Neuromuscular blocking agents (NMBAs) remain the leading cause of perioperative anaphylaxis in Australia. Standard evaluation comprises history, skin tests, and in vitro specific immunoglobulin E tests. Drug provocation tests to suspected NMBA culprits are associated… read more here.
Keywords: neuromuscular blocking; blocking agents; perioperative anaphylaxis; standard evaluation ... See more keywords
Evaluation of sedatives, analgesics, and neuromuscular blocking agents in adults receiving extracorporeal membrane oxygenation☆, ☆☆
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Critical Care"
DOI: 10.1016/j.jcrc.2016.07.020
Abstract: Purpose: The objective of this study was to evaluate the use of sedative, analgesic, and neuromuscular blocking agents (NMBAs) in patients undergoing extracorporeal membrane oxygenation (ECMO) support. Materials and methods: This was a 2‐year, prospective,… read more here.
Keywords: neuromuscular blocking; blocking agents; median daily; extracorporeal membrane ... See more keywords
Flexible organic frameworks sequester neuromuscular blocking agents in vitro and reverse neuromuscular block in vivo
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc02456j
Abstract: Supramolecular sequestration and reversal of neuromuscular block (NMB) have great clinical applications. Water-soluble flexible organic frameworks (FOFs) cross-linked by disulfide bonds are designed and prepared. Different linker lengths are introduced to FOFs to give them… read more here.
Keywords: blocking agents; organic frameworks; flexible organic; neuromuscular blocking ... See more keywords
Prone Positioning and Neuromuscular Blocking Agents as Adjunctive Therapies in Mechanically Ventilated Patients with Acute Respiratory Distress Syndrome.
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in respiratory and critical care medicine"
DOI: 10.1055/s-0042-1744304
Abstract: Neuromuscular blocking agents (NMBAs) and prone position (PP) are two major adjunctive therapies that can improve outcome in moderate-to-severe acute respiratory distress syndrome. NMBA should be used once lung-protective mechanical ventilation has been set, for… read more here.
Keywords: adjunctive therapies; blocking agents; neuromuscular blocking; respiratory distress ... See more keywords
The future of neuromuscular blocking agents.
Sign Up to like & getrecommendations! Published in 2020 at "Current Opinion in Anaesthesiology"
DOI: 10.1097/aco.0000000000000891
Abstract: PURPOSE OF REVIEW The present review provides a summary of the literature on recent development of new neuromuscular blocking agents and presents clinically well established and new reversal agents. RECENT FINDINGS Anesthesiologists are still waiting… read more here.
Keywords: anaesthesiology; blocking agents; future neuromuscular; neuromuscular blocking ... See more keywords
Pharmacokinetic/Pharmacodynamic Model of CW002, an Investigational Intermediate Neuromuscular Blocking Agent, in Healthy Volunteers
Sign Up to like & getrecommendations! Published in 2018 at "Anesthesiology"
DOI: 10.1097/aln.0000000000002157
Abstract: Background: CW002 is an investigational nondepolarizing, neuromuscular blocking agent with a rapid onset and intermediate duration of action in animals. This is a single ascending dose, healthy subject study exploring tolerability, pharmacokinetics, and potency. Methods:… read more here.
Keywords: blocking agent; neuromuscular blocking; model; cw002 investigational ... See more keywords
Neuromuscular blocking agent induced hypersensitivity reaction exploration: an update
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Anaesthesiology"
DOI: 10.1097/eja.0000000000001765
Abstract: Acute hypersensitivity reactions (AHRs) occurring in present-day anaesthesia can have severe, sometimes fatal, consequences and their incidence is increasing. The most frequent allergens responsible for AHR during anaesthesia are neuromuscular blocking agents (NMBAs) (70% of… read more here.
Keywords: agent induced; blocking agent; neuromuscular blocking; anaesthetic procedures ... See more keywords
Effects of the use of neuromuscular blocking agents on acute respiratory distress syndrome outcomes: A systematic review.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Association of Nurse Practitioners"
DOI: 10.1097/jxx.0000000000000081
Abstract: Background and purpose: Acute respiratory distress syndrome (ARDS) is a high-mortality disease with limited treatment options. Optimization of gas exchange while limiting damage to the lungs is key. The use of neuromuscular blocking agents may… read more here.
Keywords: neuromuscular blocking; blocking agents; distress syndrome; acute respiratory ... See more keywords
Documenting facemask ventilation before administering neuromuscular blocking drugs
Sign Up to like & getrecommendations! Published in 2018 at "Anaesthesia"
DOI: 10.1111/anae.14235
Abstract: Solt esz et al.'s findings confirm numerous previous findings documenting improved facemask ventilation (FMV) following administration of neuromuscular blocking (NMB) drugs [1]. Despite their unequivocal results, the authors conclude that “checking the ability to mask… read more here.
Keywords: spontaneous respiration; administration; neuromuscular blocking; facemask ventilation ... See more keywords