[From neuromyelitis optica to neuromyelitis optica spectrum disorder: from clinical syndrome to diagnistic classification].
Sign Up to like & getrecommendations! Published in 2021 at "Der Nervenarzt"
DOI: 10.1007/s00115-021-01098-w
Abstract: Neuromyelitis optica spectrum disorder (NMOSD), derived from NMO or Devic's disease, is considered as a distinct disease since the discovery of a novel and pathogenic serum autoantibody targeting aquaporin‑4 (AQP4-IgG) and is distinguished from classical multiple sclerosis… read more here.
Keywords: neuromyelitis; spectrum disorder; neuromyelitis optica; optica spectrum ... See more keywords
Diagnosis and management of neuromyelitis optica spectrum disorders - An update.
Sign Up to like & getrecommendations! Published in 2018 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2018.01.001
Abstract: Neuromyelitis optica (NMO) and Neuromyelitis optica spectrum disorders (NMOSD) are a group of autoimmune conditions characterized by inflammatory involvement of the optic nerve, spinal cord and central nervous system. Novel evidence showed a key role… read more here.
Keywords: spectrum disorders; neuromyelitis; neuromyelitis optica; management ... See more keywords
Post herpes zoster infection neuromyelitis optica spectrum disorder.
Sign Up to like & getrecommendations! Published in 2017 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2017.09.022
Abstract: Neuromyelitis optica is a severe autoimmune demyelinating disease; however, the trigger for autoimmunity in an individual patient is unclear. Here, we report the case of a 48 year old female presenting with longitudinally extensive transverse… read more here.
Keywords: zoster infection; neuromyelitis; herpes zoster; neuromyelitis optica ... See more keywords
Neuromyelitis optica and neuromyelitis optica spectrum disorders
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Neurology"
DOI: 10.1097/wco.0000000000000455
Abstract: Purpose of review The discovery of highly specific auto-antibodies directed against the water channel aquaporin 4 was a quantum leap in the definition, classification and management of neuromyelitis optica (NMO). Herein, we propose an update… read more here.
Keywords: neuromyelitis optica; spectrum disorders; optica neuromyelitis; neuromyelitis ... See more keywords
Neuromyelitis optica: an elusive cause of dysphagia
Sign Up to like & getrecommendations! Published in 2019 at "BMJ Case Reports"
DOI: 10.1136/bcr-2018-227041
Abstract: Neuromyelitis optica spectrum disorder (NMOSD) is a rare neurological condition infrequently associated with dysphagia on initial presentation. We describe the case of a 54-year-old woman who presented multiple times to healthcare professionals with severe vomiting,… read more here.
Keywords: optica elusive; neuromyelitis; cause dysphagia; neuromyelitis optica ... See more keywords
Neuromyelitis optica as a cause of serious ventilatory compromise
Sign Up to like & getrecommendations! Published in 2020 at "Postgraduate Medical Journal"
DOI: 10.1136/postgradmedj-2020-138472
Abstract: The spectrum of diseases of optic neuromyelitis corresponds to a set of rare inflammatory and autoimmune diseases of the central nervous system (CNS), with consequent demyelination of CNS neurons that predominantly affects the spinal cord,… read more here.
Keywords: optica cause; neuromyelitis; neuromyelitis optica; ventilatory compromise ... See more keywords
A Comparison of Pediatric- and Adult-Onset Aquaporin-4 Immunoglobulin G–Positive Neuromyelitis Optica Spectrum Disorder: A Review of Clinical and Radiographic Characteristics
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Child Neurology"
DOI: 10.1177/08830738221103085
Abstract: Background The identification of immunoglobulin G antibodies against the aquaporin-4 channel (AQP-IgG) in the majority of adult patients differentiates neuromyelitis optica as a distinct disease entity. The high specificity of AQP4-IgG for neuromyelitis optica has… read more here.
Keywords: neuromyelitis optica; spectrum disorder; neuromyelitis; optica spectrum ... See more keywords
Targeting chemoattractant chemokine (C–C motif) ligand 2 derived from astrocytes is a promising therapeutic approach in the treatment of neuromyelitis optica spectrum disorders
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1144532
Abstract: Introduction Aquaporin-4 immunoglobulin G (AQP4-IgG)-induced astrocytes injury is a key mechanism in the pathogenesis of neuromyelitis spectrum disorder (NMOSD), and although CCL2 is involved, its specific role has not been reported. We aimed to further… read more here.
Keywords: ccl2; igg induced; aqp4 igg; spectrum ... See more keywords
Concomitant abducens and facial nerve palsies: A rare presentation in anti-aquaporin-4 antibody-positive neuromyelitis optica
Sign Up to like & getrecommendations! Published in 2020 at "Taiwan Journal of Ophthalmology"
DOI: 10.4103/tjo.tjo_69_19
Abstract: Over the past decade, the discovery of disease-specific aquaporin-4 antibodies has led to a better understanding of the diverse spectrum of disorders that are associated with neuromyelitis optica. Brainstem manifestations have been increasingly recognized in… read more here.
Keywords: neuromyelitis optica; anti aquaporin; nerve palsies; neuromyelitis ... See more keywords