Taurine inhibits neuron apoptosis in hippocampus of diabetic rats and high glucose exposed HT-22 cells via the NGF-Akt/Bad pathway
Sign Up to like & getrecommendations! Published in 2019 at "Amino Acids"
DOI: 10.1007/s00726-019-02810-6
Abstract: Type 2 Diabetes causes learning and memory deficits that might be mediated by hippocampus neuron apoptosis. Studies found that taurine might improve cognitive deficits under diabetic condition because of its ability to prevent hippocampus neuron… read more here.
Keywords: hippocampus; apoptosis; neuron apoptosis; ngf akt ... See more keywords
LncRNA FTX inhibits hippocampal neuron apoptosis by regulating miR-21-5p/SOX7 axis in a rat model of temporal lobe epilepsy.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.03.019
Abstract: Emerging evidence has shown that long noncoding RNA (LncRNA) is involved in the development of epileptogenesis. However, the expression profile and the biological function of FTX in epilepsy remains unclear. This study aimed to provide… read more here.
Keywords: sox7 axis; apoptosis; neuron apoptosis; mir sox7 ... See more keywords
The molecular mechanism underlying mitophagy‐mediated hippocampal neuron apoptosis in diabetes‐related depression
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.16763
Abstract: Diabetes‐related depression (DD) is a major complication of diabetes mellitus. Our previous studies indicated that glutamate (Glu) and hippocampal neuron apoptosis are key signal and direct factor leading to diabetes‐related depression, respectively. However, the accurate… read more here.
Keywords: apoptosis; related depression; neuron apoptosis; hippocampal neuron ... See more keywords
Enhancement of miR-16-5p on spinal cord injury-induced neuron apoptosis and inflammatory response through inactivating ERK1/2 pathway.
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DOI: 10.23736/s0390-5616.20.04880-8
Abstract: BACKGROUND To explore the effect and mechanism of miR-16-5p on neuron apoptosis and inflammatory response induced by spinal cord injury (SCI). METHODS Allen's weight-drop method and Basso Bcattie Bresnahan (BBB) rating scale were used to… read more here.
Keywords: inflammatory response; neuron apoptosis; mir; expression ... See more keywords
m6A Methyltransferase METTL3 Reduces Hippocampal Neuron Apoptosis in a Mouse Model of Autism Through the MALAT1/SFRP2/Wnt/β-catenin Axis
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DOI: 10.30773/pi.2021.0370
Abstract: Objective Hippocampal neuron apoptosis contributes to autism, while METTL3 has been documented to possess great potentials in neuron apoptosis. Our study probed into the role of METTL3 in neuron apoptosis in autism and to determine… read more here.
Keywords: autism; neuron apoptosis; hippocampal neuron; wnt catenin ... See more keywords