Neuron‐Derived Misfolded α‐Synuclein in Blood: A Potential Biomarker for Parkinson's Disease?
Sign Up to like & getrecommendations! Published in 2023 at "Movement Disorders"
DOI: 10.1002/mds.29331
Abstract: To date, the clinical diagnosis of Parkinson’s disease (PD) is based on the assessment of motor and nonmotor symptoms, risk factors, and the response to levodopa. However, many patients with PD suffer from a late… read more here.
Keywords: disease; neuron derived; synuclein; parkinson disease ... See more keywords
MicroRNA expression profiles of neuron-derived extracellular vesicles in plasma from patients with amyotrophic lateral sclerosis
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2019.03.048
Abstract: Circulating microRNAs (miRNAs) in peripheral blood have been extensively investigated as biomarkers for early diagnosis and monitoring of disease progression. However, their cellular origin as well as their link to the pathophysiology, especially neurodegenerative disease,… read more here.
Keywords: extracellular vesicles; expression profiles; derived extracellular; amyotrophic lateral ... See more keywords
Neuron-derived neuropeptide Y fine-tunes the splenic immune responses
Sign Up to like & getrecommendations! Published in 2022 at "Neuron"
DOI: 10.1016/j.neuron.2022.01.010
Abstract: The nervous and immune systems are closely entwined to maintain the immune balance in health and disease. Here, we showed that LPS can activate suprarenal and celiac ganglia (SrG-CG) neurons and upregulate NPY expression in… read more here.
Keywords: splenic immune; neuropeptide fine; tunes splenic; neuron derived ... See more keywords
Neuron-derived VEGF contributes to cortical and hippocampal development independently of VEGFR1/2-mediated neurotrophism.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2019.11.016
Abstract: Vascular endothelial growth factor (VEGF) is a potent mitogen critical for angiogenesis and organogenesis. Deletion or inhibition of VEGF during development not only profoundly suppresses vascular outgrowth, but significantly affects the development and function of… read more here.
Keywords: derived vegf; contributes cortical; vegf contributes; neuron derived ... See more keywords
High NOR-1 (Neuron-Derived Orphan Receptor 1) Expression Strengthens the Vascular Wall Response to Angiotensin II Leading to Aneurysm Formation in Mice.
Sign Up to like & getrecommendations! Published in 2020 at "Hypertension"
DOI: 10.1161/hypertensionaha.120.16078
Abstract: No drug therapy has shown to limit abdominal aortic aneurysm (AAA) growth or rupture, and the understanding of the disease biology is incomplete; whereby, one challenge of vascular medicine is the development of good animal… read more here.
Keywords: expression; derived orphan; response; formation ... See more keywords
Comprehensive insights into the function and molecular and pharmacological regulation of neuron-derived orphan receptor 1, an orphan receptor
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.981490
Abstract: Neuron-derived orphan receptor 1 (NOR1), also called nuclear receptor subfamily 4 group A member 3 (NR4A3), is a nuclear receptor belonging to the NR4A family. Since no endogenous ligand has been identified to date, NOR1… read more here.
Keywords: function; neuron derived; nor1; regulation ... See more keywords