shox2 is required for vestibular statoacoustic neuron development
Sign Up to like & getrecommendations! Published in 2022 at "Biology Open"
DOI: 10.1242/bio.059599
Abstract: ABSTRACT Homeobox genes act at the top of genetic hierarchies to regulate cell specification and differentiation during embryonic development. We identified the short stature homeobox domain 2 (shox2) transcription factor that is required for vestibular… read more here.
Keywords: required vestibular; development; neuron development; development shox2 ... See more keywords
Deficiency in the cell-adhesion molecule dscaml1 impairs hypothalamic CRH neuron development and perturbs normal neuroendocrine stress axis function
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1113675
Abstract: The corticotropin-releasing hormone (CRH)-expressing neurons in the hypothalamus are critical regulators of the neuroendocrine stress response pathway, known as the hypothalamic-pituitary-adrenal (HPA) axis. As developmental vulnerabilities of CRH neurons contribute to stress-associated neurological and behavioral… read more here.
Keywords: stress; neuron development; crh; axis ... See more keywords
Implications of Extended Inhibitory Neuron Development
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DOI: 10.3390/ijms22105113
Abstract: A prolonged developmental timeline for GABA (γ-aminobutyric acid)-expressing inhibitory neurons (GABAergic interneurons) is an amplified trait in larger, gyrencephalic animals. In several species, the generation, migration, and maturation of interneurons take place over several months,… read more here.
Keywords: implications extended; extended inhibitory; development; inhibitory neuron ... See more keywords
The Crucial Roles of Pitx3 in Midbrain Dopaminergic Neuron Development and Parkinson’s Disease-Associated Neurodegeneration
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DOI: 10.3390/ijms24108614
Abstract: The degeneration of midbrain dopaminergic (mDA) neurons, particularly in the substantia nigra pars compacta (SNc), is one of the most prominent pathological hallmarks of Parkinson’s disease (PD). To uncover the pathogenic mechanisms of mDA neuronal… read more here.
Keywords: midbrain dopaminergic; disease; parkinson disease; neuron development ... See more keywords