Three‐dimensional spheroid cell culture of human MSC‐derived neuron‐like cells: New in vitro model to assess magnetite nanoparticle‐induced neurotoxicity effects
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4292
Abstract: As nanoparticles (NPs) can access the brain and impact on CNS function, novel in vitro models for the evaluation of NPs‐induced neurotoxicity are advocated. Three‐dimensional spheroids of primary neuron‐like cells (hNLCs) of human origin have… read more here.
Keywords: cell; induced neurotoxicity; neuron like; three dimensional ... See more keywords
Exercise ameliorates high‐fat diet‐induced impairment of differentiation of adipose‐derived stem cells into neuron‐like cells in rats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26957
Abstract: Adipose‐derived stem cells (ADSCs) can differentiate into neurons under particular conditions. It remains largely unknown whether this differentiation potential is affected by physical conditions such as obesity, which modulates the functions of adipose tissue. In… read more here.
Keywords: hfd; adscs; like cells; differentiation ... See more keywords
Conversion of Neural Stem Cells into Functional Neuron-Like Cells by MicroRNA-218: Differential Expression of Functionality Genes
Sign Up to like & getrecommendations! Published in 2020 at "Neurotoxicity Research"
DOI: 10.1007/s12640-020-00244-7
Abstract: Conversion of mesenchymal stem cells (MSC) into neuron-like cells (NLC) is a feasible cell therapy strategy for replacing lost neurons in neuronal disorders. In this study, adipose-derived MSC (ADMSC) were converted into neural stem cells… read more here.
Keywords: functionality; like cells; expression; stem ... See more keywords
A high-performance thermal conductive and outstanding electrical insulating composite based on robust neuron-like microstructure
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2021.131280
Abstract: Abstract Owing to the rapid development of highly integrated electronic devices, research on reliable and efficient Thermal interface materials (TIMs) has promising prospects. Boron nitride (BN) is regarded as an excellent functional filler due to… read more here.
Keywords: neuron like; like microstructure; performance; robust neuron ... See more keywords
Neuron like Si-carbon nanotubes composite as a high-rate anode of lithium ion batteries
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Alloys and Compounds"
DOI: 10.1016/j.jallcom.2019.02.186
Abstract: Abstract An in-situ formed neuron-like Si-CNT composite is realized with a modified chemical vapor deposition method, in which Ni(CH3COO)2 and quinolinic acid serve as catalyst and the carbon source, respectively. Under Ar/H2 gas-flow at 900 °C,… read more here.
Keywords: neuron like; cnt; carbon nanotubes; rate ... See more keywords
Piezotronic Effect Determined Neuron-Like Differentiation of Adult Stem Cells Driven by Ultrasound
Sign Up to like & getrecommendations! Published in 2021 at "Nano Energy"
DOI: 10.1016/j.nanoen.2021.106634
Abstract: Abstract Electrical stimulation is an efficient approach to inducing neural differentiation of stem cells. However, most demonstrations of conventional electrical stimulation for the regulation of stem cell differentiation generally involve three components—an electrical signal generator,… read more here.
Keywords: driven ultrasound; piezotronic effect; differentiation; stem ... See more keywords
Restoration from polyglutamine toxicity after free electron laser irradiation of neuron-like cells
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.07.031
Abstract: Proteins containing an expanded polyglutamine tract tend to aggregate, leading to the neuronal damage observed in polyglutamine diseases. We recently reported that free electron laser (FEL) irradiation markedly dissociates naked polyglutamine aggregates as well as… read more here.
Keywords: irradiation; electron laser; like cells; fel irradiation ... See more keywords
Tet1 Overexpression and Decreased DNA Hydroxymethylation Protect Neurons Against Cell Death After Injury by Increasing Expression of Genes Involved in Cell Survival.
Sign Up to like & getrecommendations! Published in 2019 at "World neurosurgery"
DOI: 10.1016/j.wneu.2019.02.133
Abstract: BACKGROUND Spinal cord and neuron injury result in loss of muscle function, sensation, or autonomic function in the body. Tet1 produces 5-hydroxymethylcytosin. The conversion was proposed as the initial step of deoxyribonucleic acid demethylation in… read more here.
Keywords: like cells; expression; injury; tet1 overexpression ... See more keywords
Bioinspired neuron-like electronics
Sign Up to like & getrecommendations! Published in 2019 at "Nature Materials"
DOI: 10.1038/s41563-019-0292-9
Abstract: As an important application of functional biomaterials, neural probes have contributed substantially to studying the brain. Bioinspired and biomimetic strategies have begun to be applied to the development of neural probes, although these and previous… read more here.
Keywords: like electronics; bioinspired neuron; neural probes; brain ... See more keywords
TNF inhibits catecholamine production from induced sympathetic neuron-like cells in rheumatoid arthritis and osteoarthritis in vitro
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-27927-8
Abstract: Synovial adipose stem cells (sASC) can be differentiated into catecholamine-expressing sympathetic neuron-like cells to treat experimental arthritis. However, the pro-inflammatory tumor necrosis factor (TNF) is known to be toxic to catecholaminergic cells (see Parkinson disease),… read more here.
Keywords: like cells; neuron; sympathetic neuron; rheumatoid arthritis ... See more keywords
Single-cell RNA sequencing uncovers a neuron-like macrophage subset associated with cancer pain
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abn5535
Abstract: Tumor innervation is a common phenomenon with unknown mechanism. Here, we discovered a direct mechanism of tumor-associated macrophage (TAM) for promoting de novo neurogenesis via a subset showing neuronal phenotypes and pain receptor expression associated… read more here.
Keywords: associated cancer; neuron like; single cell; macrophage ... See more keywords