Relative neuron loss in hippocampal sclerosis of aging and Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Neurology"
DOI: 10.1002/ana.25344
Abstract: To characterize the pattern of neuron loss in hippocampal sclerosis of aging (HS‐Aging) and age‐related diseases and to evaluate its contribution to cognitive impairment in the elderly. read more here.
Keywords: sclerosis aging; hippocampal sclerosis; loss hippocampal; neuron loss ... See more keywords
Spatial T-maze identifies cognitive deficits in piglets 1 month after hypoxia-ischemia in a model of hippocampal pyramidal neuron loss and interneuron attrition
Sign Up to like & getrecommendations! Published in 2019 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2019.111921
Abstract: Neonatal brain injury from hypoxia-ischemia (HI) causes major morbidity. Piglet HI is an established method for testing neuroprotective treatments in large, gyrencephalic brain. Though many neurobehavior tests exist for rodents, such tests and their associations… read more here.
Keywords: neuron loss; interneuron; spatial maze; loss ... See more keywords
Participation of perforin in mediating dopaminergic neuron loss in MPTP-induced Parkinson's disease in mice.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.01.150
Abstract: Both resident innate and peripheral immune aberrations have been demonstrated to influence Parkinson's disease (PD) progression. However, it is still enigmatic how and which immune components are lethal to the dopaminergic neuron in PD. We… read more here.
Keywords: mptp; dopaminergic neuron; mice; parkinson disease ... See more keywords
Single low doses of MPTP decrease tyrosine hydroxylase expression in the absence of overt neuron loss
Sign Up to like & getrecommendations! Published in 2017 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2017.03.008
Abstract: HIGHLIGHTSLow doses of MPTP cause loss of TH expression rather than actual loss of neurons.Higher doses of MPTP cause both loss of TH expression and neurons.Striatal dopamine levels and terminal marker loss are consistent with… read more here.
Keywords: loss; dopamine; doses mptp; expression ... See more keywords
A Critical Analysis of Intestinal Enteric Neuron Loss and Constipation in Parkinson’s Disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Parkinson's Disease"
DOI: 10.3233/jpd-223262
Abstract: Constipation afflicts many patients with Parkinson’s disease (PD) and significantly impacts on patient quality of life. PD-related constipation is caused by intestinal dysfunction, but the etiology of this dysfunction in patients is unknown. One possible… read more here.
Keywords: parkinson disease; neuron loss; loss; constipation ... See more keywords
Effects of Caloric Restriction on Spatial Object Recognition Memory, Hippocampal Neuron Loss and Neuroinflammation in Aged Rats
Sign Up to like & getrecommendations! Published in 2023 at "Nutrients"
DOI: 10.3390/nu15071572
Abstract: Age-related neurobiological changes significantly affect hippocampal structure and function, such that the main cognitive impairments associated with aging are related to the integrity of this brain structure, including the deterioration in spatial object recognition (SOR)… read more here.
Keywords: hippocampal neuron; spatial object; neuron loss; loss ... See more keywords