Unidirectional neuronal cell growth and differentiation on aligned polyhydroxyalkanoate blend microfibres with varying diameters
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2911
Abstract: Polyhydroxyalkanoates (PHAs) are a family of prokaryotic‐derived biodegradable and biocompatible natural polymers known to exhibit neuroregenerative properties. In this work, poly(3‐hydroxybutyrate), P(3HB), and poly(3‐hydroxyoctanoate), P(3HO), have been combined to form blend fibres for directional guidance… read more here.
Keywords: neuronal cell; blend; differentiation; growth differentiation ... See more keywords
Astrocytes in Huntington's Disease.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-9913-8_14
Abstract: Huntington's disease (HD) is a dominantly inherited neurodegenerative disease that results in motor, cognitive and psychiatric dysfunction. It is caused by a polyglutamine repeat expansion mutation in the widely expressed HTT protein. The clinical manifestations… read more here.
Keywords: huntington disease; neuronal cell; disease; cell types ... See more keywords
Mechanotransduction in neuronal cell development and functioning
Sign Up to like & getrecommendations! Published in 2019 at "Biophysical Reviews"
DOI: 10.1007/s12551-019-00587-2
Abstract: Although many details remain still elusive, it became increasingly evident in recent years that mechanosensing of microenvironmental biophysical cues and subsequent mechanotransduction are strongly involved in the regulation of neuronal cell development and functioning. This… read more here.
Keywords: cell development; neuronal cell; mechanotransduction; development functioning ... See more keywords
Protection against RAGE-mediated neuronal cell death by sRAGE-secreting human mesenchymal stem cells in 5xFAD transgenic mouse model
Sign Up to like & getrecommendations! Published in 2017 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2017.07.158
Abstract: Alzheimer's disease (AD), which is the most commonly encountered neurodegenerative disease, causes synaptic dysfunction and neuronal loss due to various pathological processes that include tau abnormality and amyloid beta (Aβ) accumulation. Aβ stimulates the secretion… read more here.
Keywords: neuronal cell; srage; rage; cell death ... See more keywords
Neuronal cell types in the annelid Platynereis dumerilii
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2018.12.008
Abstract: The marine annelid Platynereis dumerilii is an invertebrate laboratory model for developmental biology and neuroscience. Its larval stages are small and transparent, enabling whole-body analyses of cell-type diversity and neuronal circuits. Here, we review the… read more here.
Keywords: annelid platynereis; neuronal cell; cell types; platynereis dumerilii ... See more keywords
Viral vectors for neuronal cell type-specific visualization and manipulations
Sign Up to like & getrecommendations! Published in 2020 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2020.03.011
Abstract: Characterizing neuronal cell types demands efficient strategies for specific labeling and manipulation of individual subtypes to dissect their connectivity and functions. Recombinant viral technology offers a powerful toolbox for targeted transgene expression in specific neuronal… read more here.
Keywords: viral vectors; type specific; neuronal cell; cell ... See more keywords
miR-16-5p is upregulated by amyloid β deposition in Alzheimer's disease models and induces neuronal cell apoptosis through direct targeting and suppression of BCL-2
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2020.110954
Abstract: Alzheimer's disease (AD) is the most common form of dementia with irreversible neurodegeneration. Accumulation of amyloid beta (Aβ) in the brain is considered to be a major cause of neuronal cell death in AD, but… read more here.
Keywords: alzheimer disease; neuronal cell; mir; cell apoptosis ... See more keywords
Quantitative models of feline lumbosacral dorsal root ganglia neuronal cell density
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroscience Methods"
DOI: 10.1016/j.jneumeth.2017.07.018
Abstract: BACKGROUND Dorsal root ganglia (DRG) are spinal root components that contain the cell bodies of converging primary sensory neurons. DRG are becoming a therapeutic target for electrical neural interfaces. Our purpose was to establish methods… read more here.
Keywords: dorsal root; root ganglia; neuronal cell; density ... See more keywords
Regulatory mechanism of cyclins and cyclin-dependent kinases in post-mitotic neuronal cell division.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.120006
Abstract: Neurodegenerative diseases (NDDs) are the most common life-threatening disease of the central nervous system and it cause the progressive loss of neuronal cells. The exact mechanism of the disease's progression is not clear and thus… read more here.
Keywords: mechanism; neuronal cell; cell cycle; cell division ... See more keywords
SN56 neuronal cell death after 24 h and 14 days chlorpyrifos exposure through glutamate transmission dysfunction, increase of GSK-3β enzyme, β-amyloid and tau protein levels.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology"
DOI: 10.1016/j.tox.2018.04.003
Abstract: Chlorpyrifos (CPF) is an organophosphate insecticide described to induce cognitive disorders, both after acute and repeated administration. However, the mechanisms through which it induces these effects are unknown. CPF has been reported to produce basal… read more here.
Keywords: transmission; neuronal cell; cell death; cpf ... See more keywords
Neuronal cell-type classification: challenges, opportunities and the path forward
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Neuroscience"
DOI: 10.1038/nrn.2017.85
Abstract: Neurons have diverse molecular, morphological, connectional and functional properties. We believe that the only realistic way to manage this complexity — and thereby pave the way for understanding the structure, function and development of brain… read more here.
Keywords: classification; neuronal cell; type classification; cell ... See more keywords