Serum Neurofilament light: A biomarker of neuronal damage in multiple sclerosis
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Neurology"
DOI: 10.1002/ana.24954
Abstract: Neurofilament light chains (NfL) are unique to neuronal cells, are shed to the cerebrospinal fluid (CSF), and are detectable at low concentrations in peripheral blood. Various diseases causing neuronal damage have resulted in elevated CSF… read more here.
Keywords: neuronal damage; neurofilament light; multiple sclerosis;
Hemodynamic changes and neuronal damage detected by 9.4 T MRI in rats with chronic cerebral ischemia and cognitive impairment
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2642
Abstract: The bilateral common carotid artery occlusion (BCCAO) rat model is an ideal animal model for simulating the pathology of chronic brain hypoperfusion in humans. However, dynamic changes in neuronal activity, cellular edema, and neuronal structural… read more here.
Keywords: damage detected; hemodynamic changes; mri rats; neuronal damage ... See more keywords
Glycine receptors are involved in hippocampal neuronal damage caused by oxygen‐glucose deficiency
Sign Up to like & getrecommendations! Published in 2018 at "Cell Biology International"
DOI: 10.1002/cbin.11034
Abstract: Glycine receptors (GlyRs) belong to the family of ligand‐gated cys‐loop receptors and effectuate fast inhibitory neurotransmission in central nervous system (CNS). They are involved in numerous physiological processes, such as movement, respiration, and processing of… read more here.
Keywords: neuronal damage; glycine receptors; glucose deficiency; oxygen glucose ... See more keywords
Neurological symptoms and neuronal damage markers in acute COVID‐19: Is there a correlation? A pilot study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28240
Abstract: A wide spectrum of neurological symptoms (NS) has been described in patients with COVID‐19. We examined the plasma levels of neuron‐specific enolase (NSE) and neurofilament light chain (NFL) together, as neuronal damage markers, and their… read more here.
Keywords: neurological symptoms; neuronal damage; acute covid; nfl levels ... See more keywords
Neuronal damage and neuroinflammation markers in patients with autoimmune encephalitis and multiple sclerosis
Sign Up to like & getrecommendations! Published in 2019 at "Metabolic Brain Disease"
DOI: 10.1007/s11011-019-00452-x
Abstract: Inflammatory diseases of the central nervous system (CNS) are a diagnostic challenge to clinicians. Autoimmune encephalitis (AE) is an important diagnostic consideration in patients with CNS inflammatory disorders; despite of a wide range of neuropsychiatric… read more here.
Keywords: autoimmune encephalitis; neuronal damage; neuroinflammation; group ... See more keywords
Neuron-specific enolase levels as a marker for possible neuronal damage in idiopathic intracranial hypertension
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neurologica Belgica"
DOI: 10.1007/s13760-017-0762-2
Abstract: Although formerly considered as a “benign” disease, the presence of some important problems such as vision loss, resistance to appropriate medical treatment and relapses suggests that neuronal damage might play a role in the pathophysiology… read more here.
Keywords: neuronal damage; nse levels; possible neuronal; neuron specific ... See more keywords
Sodium influx through cerebral sodium‐glucose transporter type 1 exacerbates the development of cerebral ischemic neuronal damage
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2017.02.007
Abstract: Abstract We recently reported that cerebral sodium‐glucose transporter type 1 (SGLT‐1) plays a role in exacerbation of cerebral ischemia. However, the mechanism by which cerebral SGLT‐1 acts remains unclear. Here we demonstrated that sodium influx… read more here.
Keywords: cerebral ischemic; neuronal damage; glucose; sodium ... See more keywords
NADPH oxidase 2‐mediated NLRP1 inflammasome activation involves in neuronal senescence in hippocampal neurons in vitro
Sign Up to like & getrecommendations! Published in 2019 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2019.01.025
Abstract: &NA; Oxidative stress and inflammation are closely related to neuron ageing. NADPH oxidase 2 (NOX2) is a major source of reactive oxygen species (ROS) generation in brain. The nucleotide‐binding oligomerisation domain (NOD)‐like receptor protein 1… read more here.
Keywords: nadph oxidase; nlrp1 inflammasome; hippocampal neurons; neuronal damage ... See more keywords
Hyperoside alleviates epilepsy-induced neuronal damage by enhancing antioxidant levels and reducing autophagy.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.112884
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Hypericum perforatum L. (genus Hypericum, family Hypericaceae), a plant commonly used in traditional Chinese medicine, is believed to confer a wide range of benefits, including fever reduction, detoxification, calming, and pain relief via… read more here.
Keywords: neuronal damage; induced neuronal; epilepsy induced; group ... See more keywords
Mismatch between GLUTs and glucose levels causes neuronal damage during glucose fluctuations.
Sign Up to like & getrecommendations! Published in 2018 at "Medical hypotheses"
DOI: 10.1016/j.mehy.2018.01.010
Abstract: Abnormal glucose levels damage the central nervous system, especially in case of rapid fluctuations. Even a single episode of glucose reperfusion can result in overt impairment of neurons. Oxidative stress plays an important role in… read more here.
Keywords: neuronal damage; glucose levels; mismatch gluts; glucose fluctuations ... See more keywords
Agomelatine protects against neuronal damage without preventing epileptogenesis in the kainate model of temporal lobe epilepsy
Sign Up to like & getrecommendations! Published in 2017 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2017.04.017
Abstract: Recent studies about the novel antidepressant agomelatine, which is a mixed MT1 and MT2 melatonin receptor agonist and 5HT2C serotonin receptor antagonist possessing an anticonvulsant and neuroprotective action, suggest that it may have potential to… read more here.
Keywords: epilepsy; neuronal damage; lobe epilepsy; epileptogenesis ... See more keywords