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   Articles with "neuronal damage" as a keyword



Serum Neurofilament light: A biomarker of neuronal damage in multiple sclerosis

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recommendations! Published in 2017 at "Annals of Neurology"

DOI: 10.1002/ana.24954

Abstract: Neurofilament light chains (NfL) are unique to neuronal cells, are shed to the cerebrospinal fluid (CSF), and are detectable at low concentrations in peripheral blood. Various diseases causing neuronal damage have resulted in elevated CSF… read more here.

Keywords: neuronal damage; neurofilament light; multiple sclerosis;

Hemodynamic changes and neuronal damage detected by 9.4 T MRI in rats with chronic cerebral ischemia and cognitive impairment

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recommendations! Published in 2022 at "Brain and Behavior"

DOI: 10.1002/brb3.2642

Abstract: The bilateral common carotid artery occlusion (BCCAO) rat model is an ideal animal model for simulating the pathology of chronic brain hypoperfusion in humans. However, dynamic changes in neuronal activity, cellular edema, and neuronal structural… read more here.

Keywords: damage detected; hemodynamic changes; mri rats; neuronal damage ... See more keywords

Glycine receptors are involved in hippocampal neuronal damage caused by oxygen‐glucose deficiency

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recommendations! Published in 2018 at "Cell Biology International"

DOI: 10.1002/cbin.11034

Abstract: Glycine receptors (GlyRs) belong to the family of ligand‐gated cys‐loop receptors and effectuate fast inhibitory neurotransmission in central nervous system (CNS). They are involved in numerous physiological processes, such as movement, respiration, and processing of… read more here.

Keywords: neuronal damage; glycine receptors; glucose deficiency; oxygen glucose ... See more keywords

Neurological symptoms and neuronal damage markers in acute COVID‐19: Is there a correlation? A pilot study

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recommendations! Published in 2022 at "Journal of Medical Virology"

DOI: 10.1002/jmv.28240

Abstract: A wide spectrum of neurological symptoms (NS) has been described in patients with COVID‐19. We examined the plasma levels of neuron‐specific enolase (NSE) and neurofilament light chain (NFL) together, as neuronal damage markers, and their… read more here.

Keywords: neurological symptoms; neuronal damage; acute covid; nfl levels ... See more keywords
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Vitexin Alleviates Kainic Acid-Induced Seizure Through Inhibiting P2X7R/NLRP3 Signaling Pathway.

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recommendations! Published in 2025 at "Inflammation"

DOI: 10.1007/s10753-025-02324-2

Abstract: Epilepsy, a prevalent chronic brain disorder, remains inadequately controlled by current antiepileptic drugs. Neuroinflammation is considered a crucial component in the process of epileptogenesis. Vitexin (VT), primarily derived from medicinal plants, is a flavonoid monomer… read more here.

Keywords: inhibiting p2x7r; kainic acid; p2x7r nlrp3; induced seizure ... See more keywords

Neuronal damage and neuroinflammation markers in patients with autoimmune encephalitis and multiple sclerosis

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recommendations! Published in 2019 at "Metabolic Brain Disease"

DOI: 10.1007/s11011-019-00452-x

Abstract: Inflammatory diseases of the central nervous system (CNS) are a diagnostic challenge to clinicians. Autoimmune encephalitis (AE) is an important diagnostic consideration in patients with CNS inflammatory disorders; despite of a wide range of neuropsychiatric… read more here.

Keywords: autoimmune encephalitis; neuronal damage; neuroinflammation; group ... See more keywords

Neuron-specific enolase levels as a marker for possible neuronal damage in idiopathic intracranial hypertension

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recommendations! Published in 2017 at "Acta Neurologica Belgica"

DOI: 10.1007/s13760-017-0762-2

Abstract: Although formerly considered as a “benign” disease, the presence of some important problems such as vision loss, resistance to appropriate medical treatment and relapses suggests that neuronal damage might play a role in the pathophysiology… read more here.

Keywords: neuronal damage; nse levels; possible neuronal; neuron specific ... See more keywords

Sodium influx through cerebral sodium‐glucose transporter type 1 exacerbates the development of cerebral ischemic neuronal damage

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recommendations! Published in 2017 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2017.02.007

Abstract: Abstract We recently reported that cerebral sodium‐glucose transporter type 1 (SGLT‐1) plays a role in exacerbation of cerebral ischemia. However, the mechanism by which cerebral SGLT‐1 acts remains unclear. Here we demonstrated that sodium influx… read more here.

Keywords: cerebral ischemic; neuronal damage; glucose; sodium ... See more keywords

NADPH oxidase 2‐mediated NLRP1 inflammasome activation involves in neuronal senescence in hippocampal neurons in vitro

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recommendations! Published in 2019 at "International Immunopharmacology"

DOI: 10.1016/j.intimp.2019.01.025

Abstract: &NA; Oxidative stress and inflammation are closely related to neuron ageing. NADPH oxidase 2 (NOX2) is a major source of reactive oxygen species (ROS) generation in brain. The nucleotide‐binding oligomerisation domain (NOD)‐like receptor protein 1… read more here.

Keywords: nadph oxidase; nlrp1 inflammasome; hippocampal neurons; neuronal damage ... See more keywords
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Hyperoside alleviates epilepsy-induced neuronal damage by enhancing antioxidant levels and reducing autophagy.

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recommendations! Published in 2020 at "Journal of ethnopharmacology"

DOI: 10.1016/j.jep.2020.112884

Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Hypericum perforatum L. (genus Hypericum, family Hypericaceae), a plant commonly used in traditional Chinese medicine, is believed to confer a wide range of benefits, including fever reduction, detoxification, calming, and pain relief via… read more here.

Keywords: neuronal damage; induced neuronal; epilepsy induced; group ... See more keywords

Mismatch between GLUTs and glucose levels causes neuronal damage during glucose fluctuations.

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recommendations! Published in 2018 at "Medical hypotheses"

DOI: 10.1016/j.mehy.2018.01.010

Abstract: Abnormal glucose levels damage the central nervous system, especially in case of rapid fluctuations. Even a single episode of glucose reperfusion can result in overt impairment of neurons. Oxidative stress plays an important role in… read more here.

Keywords: neuronal damage; glucose levels; mismatch gluts; glucose fluctuations ... See more keywords