Role of Phosphatidylinositol-3 Kinase Pathway in NMDA Preconditioning: Different Mechanisms for Seizures and Hippocampal Neuronal Degeneration Induced by Quinolinic Acid
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DOI: 10.1007/s12640-018-9903-5
Abstract: N-methyl D-aspartate (NMDA) preconditioning is evoked by the administration of a subtoxic dose of NMDA and is protective against neuronal excitotoxicity. This effect may involve a diversity of targets and cell signaling cascades associated to… read more here.
Keywords: neuronal degeneration; phosphatidylinositol kinase; seizures hippocampal; induced quinolinic ... See more keywords
Neuronal degeneration and associated alterations in cytokine and protein in an experimental branch retinal venous occlusion model
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DOI: 10.1016/j.exer.2018.05.025
Abstract: ABSTRACT The mechanisms of neuronal degeneration and associated acute alterations in intraretinal cytokine and protein levels remain poorly understood in variable ischaemic retinopathies such as in branch retinal vein occlusion (BRVO). Herein we investigate neuronal… read more here.
Keywords: neuronal degeneration; cytokine protein; branch retinal; model ... See more keywords
Metabolic aspects of neuronal degeneration: From a NAD+ point of view
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DOI: 10.1016/j.neures.2018.07.001
Abstract: Cellular metabolism maintains the life of cells, allowing energy production required for building cellular constituents and maintaining homeostasis under constantly changing external environments. Neuronal cells maintain their structure and function for the entire life of… read more here.
Keywords: neuronal degeneration; metabolic aspects; nad point; aspects neuronal ... See more keywords
Sphingolipids and neuronal degeneration in lysosomal storage disorders
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DOI: 10.1111/jnc.14540
Abstract: Ceramide, sphingomyelin, and glycosphingolipids (both neutral and acidic) are characterized by the presence in the lipid moiety of an aliphatic base known as sphingosine. Altogether, they are called sphingolipids and are particularly abundant in neuronal… read more here.
Keywords: storage; lysosomal storage; neuronal degeneration; sphingolipids neuronal ... See more keywords