SOX‐11 regulates LINE‐1 retrotransposon activity during neuronal differentiation
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Letters"
DOI: 10.1002/1873-3468.13260
Abstract: Activity of the human long interspersed nuclear elements‐1 (LINE‐1) retrotransposon occurs mainly in early embryonic development and during hippocampal neurogenesis. SOX‐11, a transcription factor relevant to neuronal development, has unknown functions in the control of… read more here.
Keywords: line retrotransposon; activity; neuronal differentiation; line ... See more keywords
Silicate Nanoplatelets Promotes Neuronal Differentiation of Neural Stem Cells and Restoration of Spinal Cord Injury.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203051
Abstract: Neural stem cell (NSC) transplantation has been suggested as a promising therapeutic strategy to replace lost neurons after spinal cord injury (SCI). However, the low survival rate and neuronal differentiation efficiency of implanted NSCs within… read more here.
Keywords: cord injury; neural stem; neuronal differentiation; spinal cord ... See more keywords
Neuronal Differentiation of LUHMES Cells Induces Substantial Changes of the Proteome
Sign Up to like & getrecommendations! Published in 2020 at "PROTEOMICS"
DOI: 10.1002/pmic.202000174
Abstract: Neuronal cell lines are important model systems to study mechanisms of neurodegenerative diseases. One example is the Lund Human Mesencephalic (LUHMES) cell line, which can differentiate into dopaminergic‐like neurons and is frequently used to study… read more here.
Keywords: luhmes cells; substantial changes; cells induces; neuronal differentiation ... See more keywords
Comparative Study of Different Acorus Species in Potentiating Neuronal Differentiation in Cultured PC12 Cells
Sign Up to like & getrecommendations! Published in 2017 at "Phytotherapy Research"
DOI: 10.1002/ptr.5904
Abstract: Acori Tatarinowii Rhizoma (ATR), the rhizome of Acorus tatarinowii Schott, is a common traditional Chinese medicine being used clinically for mental disorder. However, other Acorus species herbs are all having the same Chinese name ‘Chang… read more here.
Keywords: cultured pc12; neuronal differentiation; pc12 cells; acorus species ... See more keywords
PKA-GSK3β and β-Catenin Signaling Play a Critical Role in Trans-Resveratrol Mediated Neuronal Differentiation in Human Cord Blood Stem Cells
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0539-x
Abstract: The role of resveratrol (RV), a natural polyphenol, is well documented, although its role on neurogenesis is still controversial and poorly understood. Therefore, to decipher the cellular insights of RV on neurogenesis, we investigated the… read more here.
Keywords: cord blood; differentiation human; human cord; differentiation ... See more keywords
Increased Neuronal Differentiation of Neural Progenitor Cells Derived from Phosphovimentin-Deficient Mice
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0759-0
Abstract: Vimentin is an intermediate filament (also known as nanofilament) protein expressed in several cell types of the central nervous system, including astrocytes and neural stem/progenitor cells. Mutation of the vimentin serine sites that are phosphorylated… read more here.
Keywords: progenitor cells; differentiation; increased neuronal; differentiation neural ... See more keywords
Secretome of Differentiated PC12 Cells Enhances Neuronal Differentiation in Human Mesenchymal Stem Cells Via NGF-Like Mechanism
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-0981-4
Abstract: The secretome-mediated responses over cellular physiology are well documented. Stem cells have been ruling the field of secretomics and its role in regenerative medicine since the past few years. However, the mechanistic aspects of secretome-mediated… read more here.
Keywords: pc12 cells; stem; stem cells; differentiated pc12 ... See more keywords
NTF3 Is a Novel Target Gene of the Transcription Factor POU3F2 and Is Required for Neuronal Differentiation
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-0995-y
Abstract: POU-homeodomain transcription factor POU3F2 is a critical transcription factor that participates in neuronal differentiation. However, little is known about its downstream mediators. Here genome-wide analyses of a human neuronal differentiation cell model, NT2D1, suggested neurotrophin-3… read more here.
Keywords: transcription factor; differentiation; neuronal differentiation; pou3f2 ... See more keywords
Transcriptome Analysis of iPSC-Derived Neurons from Rubinstein-Taybi Patients Reveals Deficits in Neuronal Differentiation
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Neurobiology"
DOI: 10.1007/s12035-020-01983-6
Abstract: Rubinstein-Taybi syndrome (RSTS) is a rare multisystem developmental disorder with moderate to severe intellectual disability caused by heterozygous mutations of either CREBBP or EP300 genes encoding CBP/p300 chromatin regulators. We explored the gene programs and… read more here.
Keywords: transcriptome analysis; derived neurons; rubinstein taybi; differentiation ... See more keywords
Laminin and Platelet-Derived Growth Factor-BB Promote Neuronal Differentiation of Human Urine-Derived Stem Cells
Sign Up to like & getrecommendations! Published in 2017 at "Tissue Engineering and Regenerative Medicine"
DOI: 10.1007/s13770-017-0102-x
Abstract: Abstract Urine-derived stem cells (USCs) are considered as a promising cell source capable of neuronal differentiation. In addition, specific growth factors and extracellular matrix are essential for enhancing their neuronal differentiation efficiency. In this study,… read more here.
Keywords: differentiation; laminin; stem; growth ... See more keywords
The βγ subunit of heterotrimeric G proteins interacts with actin filaments during neuronal differentiation.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.02.095
Abstract: The βγ subunit of heterotrimeric G proteins, a key molecule in the G protein-coupled receptors (GPCRs) signaling pathway, has been shown to be an important factor in the modulation of the microtubule cytoskeleton. Gβγ has… read more here.
Keywords: subunit heterotrimeric; heterotrimeric proteins; interacts actin; actin filaments ... See more keywords