SOX‐11 regulates LINE‐1 retrotransposon activity during neuronal differentiation
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Letters"
DOI: 10.1002/1873-3468.13260
Abstract: Activity of the human long interspersed nuclear elements‐1 (LINE‐1) retrotransposon occurs mainly in early embryonic development and during hippocampal neurogenesis. SOX‐11, a transcription factor relevant to neuronal development, has unknown functions in the control of… read more here.
Keywords: line retrotransposon; activity; neuronal differentiation; line ... See more keywords
KIF5A upregulation by FAK-mediated downregulation of epigenetic modifiers promotes mitochondrial dynamics in neuronal differentiation.
Sign Up to like & getrecommendations! Published in 2025 at "FEBS letters"
DOI: 10.1002/1873-3468.70177
Abstract: Neuronal differentiation depends on mitochondrial transport and networking toward the developing axon and dendrites. Herein, we report that the motor protein kinesin family member 5A (KIF5A) is essential for neuronal maturation through regulation of mitochondrial… read more here.
Keywords: differentiation; downregulation epigenetic; epigenetic modifiers; fak ... See more keywords
Real‐Time, Non‐Invasive Monitoring of Neuronal Differentiation Using Intein‐Enabled Fluorescence Signal Translocation in Genetically Encoded Stem Cell‐Based Biosensors
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202400394
Abstract: Real‐time and non‐invasive monitoring of neuronal differentiation helps to increase understanding of neuronal development and develop stem cell therapies for neurodegenerative diseases. Conventional methods such as RT‐PCR, western blotting, and immunofluorescence (IF), lack single‐cell‐level resolution… read more here.
Keywords: differentiation; real time; stem cell; cell ... See more keywords
Silicate Nanoplatelets Promotes Neuronal Differentiation of Neural Stem Cells and Restoration of Spinal Cord Injury.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203051
Abstract: Neural stem cell (NSC) transplantation has been suggested as a promising therapeutic strategy to replace lost neurons after spinal cord injury (SCI). However, the low survival rate and neuronal differentiation efficiency of implanted NSCs within… read more here.
Keywords: cord injury; neural stem; neuronal differentiation; spinal cord ... See more keywords
Dynamic mRNA Stability Buffer Transcriptional Activation During Neuronal Differentiation and Is Regulated by SAMD4A
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.31477
Abstract: Neurons are exceptionally sensitive to oxidative stress, which is the basis for many neurodegenerative disease pathophysiologies. The posttranscriptional basis for neuronal differentiation and behavior is not well characterized. The steady‐state levels of mRNA are outcomes… read more here.
Keywords: stability; analysis; mrna stability; dynamic mrna ... See more keywords
Neuronal Differentiation of LUHMES Cells Induces Substantial Changes of the Proteome
Sign Up to like & getrecommendations! Published in 2020 at "PROTEOMICS"
DOI: 10.1002/pmic.202000174
Abstract: Neuronal cell lines are important model systems to study mechanisms of neurodegenerative diseases. One example is the Lund Human Mesencephalic (LUHMES) cell line, which can differentiate into dopaminergic‐like neurons and is frequently used to study… read more here.
Keywords: luhmes cells; substantial changes; cells induces; neuronal differentiation ... See more keywords
Comparative Study of Different Acorus Species in Potentiating Neuronal Differentiation in Cultured PC12 Cells
Sign Up to like & getrecommendations! Published in 2017 at "Phytotherapy Research"
DOI: 10.1002/ptr.5904
Abstract: Acori Tatarinowii Rhizoma (ATR), the rhizome of Acorus tatarinowii Schott, is a common traditional Chinese medicine being used clinically for mental disorder. However, other Acorus species herbs are all having the same Chinese name ‘Chang… read more here.
Keywords: cultured pc12; neuronal differentiation; pc12 cells; acorus species ... See more keywords
Joubert syndrome-derived induced pluripotent stem cells show altered neuronal differentiation in vitro
Sign Up to like & getrecommendations! Published in 2024 at "Cell and Tissue Research"
DOI: 10.1007/s00441-024-03876-9
Abstract: Joubert syndrome (JS) is a recessively inherited congenital ataxia characterized by hypotonia, psychomotor delay, abnormal ocular movements, intellectual disability, and a peculiar cerebellar and brainstem malformation, the “molar tooth sign.” Over 40 causative genes have… read more here.
Keywords: differentiation; joubert syndrome; patient derived; derived induced ... See more keywords
PKA-GSK3β and β-Catenin Signaling Play a Critical Role in Trans-Resveratrol Mediated Neuronal Differentiation in Human Cord Blood Stem Cells
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0539-x
Abstract: The role of resveratrol (RV), a natural polyphenol, is well documented, although its role on neurogenesis is still controversial and poorly understood. Therefore, to decipher the cellular insights of RV on neurogenesis, we investigated the… read more here.
Keywords: cord blood; differentiation human; human cord; differentiation ... See more keywords
Increased Neuronal Differentiation of Neural Progenitor Cells Derived from Phosphovimentin-Deficient Mice
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0759-0
Abstract: Vimentin is an intermediate filament (also known as nanofilament) protein expressed in several cell types of the central nervous system, including astrocytes and neural stem/progenitor cells. Mutation of the vimentin serine sites that are phosphorylated… read more here.
Keywords: progenitor cells; differentiation; increased neuronal; differentiation neural ... See more keywords
Secretome of Differentiated PC12 Cells Enhances Neuronal Differentiation in Human Mesenchymal Stem Cells Via NGF-Like Mechanism
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-0981-4
Abstract: The secretome-mediated responses over cellular physiology are well documented. Stem cells have been ruling the field of secretomics and its role in regenerative medicine since the past few years. However, the mechanistic aspects of secretome-mediated… read more here.
Keywords: pc12 cells; stem; stem cells; differentiated pc12 ... See more keywords