Coupling progenitor and neuronal diversity in the developing neocortex
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12846
Abstract: The adult neocortex is composed of several types of glutamatergic neurons, which are sequentially born from progenitors during development. The extent and nature of progenitor diversity, and how it relates to neuronal diversity, is still… read more here.
Keywords: progenitor neuronal; diversity; neuronal diversity; coupling progenitor ... See more keywords
Single-cell analysis of diversity in human stem cell-derived neurons
Sign Up to like & getrecommendations! Published in 2017 at "Cell and Tissue Research"
DOI: 10.1007/s00441-017-2728-3
Abstract: Neural stem and progenitor cells produce one of the most remarkable organs in nature, the human brain. Among neural stem cell progeny, post-mitotic neurons are likewise remarkably diverse. Single-cell transcriptomic approaches are now cataloging a… read more here.
Keywords: single cell; neuronal diversity; stem cell; stem ... See more keywords
Neuronal diversity and convergence in a visual system developmental atlas
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DOI: 10.1038/s41586-020-2879-3
Abstract: Deciphering how neuronal diversity is established and maintained requires a detailed knowledge of neuronal gene expression throughout development. In contrast to mammalian brains 1 , 2 , the large neuronal diversity of the Drosophila optic… read more here.
Keywords: diversity drosophila; diversity; neuronal diversity; diversity convergence ... See more keywords
Origins of neuronal diversity
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DOI: 10.1126/science.364.6440.542-k
Abstract: Neurodevelopment Although the main task of a neuroprogenitor is to produce more cells, it may not always produce the same cells. Some progenitors produce different daughter neurons as an embryo develops. Concurrently, these daughter neurons… read more here.
Keywords: neuronal diversity; science; origins neuronal; daughter neurons ... See more keywords
A crossroad of neuronal diversity to build circuitry
Sign Up to like & getrecommendations! Published in 2017 at "Science"
DOI: 10.1126/science.aan2856
Abstract: Clustered protocadherin genes control convergence and divergence of neurons One of the most important questions in brain science is how infinite information is processed and maintained by a finite number of neurons. A nearly limitless… read more here.
Keywords: diversity build; diversity; neuronal diversity; build circuitry ... See more keywords
Mapping the transcriptional diversity of genetically and anatomically defined cell populations in the mouse brain
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DOI: 10.7554/elife.38619
Abstract: Understanding the principles governing neuronal diversity is a fundamental goal for neuroscience. Here, we provide an anatomical and transcriptomic database of nearly 200 genetically identified cell populations. By separately analyzing the robustness and pattern of… read more here.
Keywords: cell populations; expression differences; mapping transcriptional; cell ... See more keywords