Thoughts on the role of endogenous D‐cysteine in neuronal function
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DOI: 10.1002/bies.202200089
Abstract: is an understudied and underappreciated endogenous amino acid in the brain. Its role in neuronal function has been understudied for years due to the difficulty in detecting it. There is recent work showing that D-cysteine… read more here.
Keywords: role endogenous; role; thoughts role; amino acid ... See more keywords
Mitochondrial calcium cycling in neuronal function and neurodegeneration
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DOI: 10.3389/fcell.2023.1094356
Abstract: Mitochondria are essential for proper cellular function through their critical roles in ATP synthesis, reactive oxygen species production, calcium (Ca2+) buffering, and apoptotic signaling. In neurons, Ca2+ buffering is particularly important as it helps to… read more here.
Keywords: function; ca2; neuronal function; mitochondrial calcium ... See more keywords
Role of piRNA biogenesis and its neuronal function in the development of neurodegenerative diseases
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DOI: 10.3389/fnagi.2023.1157818
Abstract: Neurodegenerative diseases, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS), are caused by neuronal loss and dysfunction. Despite remarkable improvements in our understanding of these pathogeneses, serious worldwide problems with… read more here.
Keywords: pirna biogenesis; biogenesis neuronal; role pirna; biogenesis ... See more keywords
The Effects of Sindbis Viral Vectors on Neuronal Function
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DOI: 10.3389/fncel.2019.00362
Abstract: Viral vectors are attractive tools to express genes in neurons. Transduction of neurons with a recombinant, replication-deficient Sindbis viral vector is a method of choice for studying the effects of short-term protein overexpression on neuronal… read more here.
Keywords: viral vectors; viral vector; sindbis viral; neuronal function ... See more keywords
Drosophila Nrf2/Keap1 Mediated Redox Signaling Supports Synaptic Function and Longevity and Impacts on Circadian Activity
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DOI: 10.3389/fnmol.2019.00086
Abstract: Many neurodegenerative conditions and age-related neuropathologies are associated with increased levels of reactive oxygen species (ROS). The cap “n” collar (CncC) family of transcription factors is one of the major cellular system that fights oxidative… read more here.
Keywords: longevity; cncc signaling; function; keap1 ... See more keywords