Nuclear Receptor NR5A2 Promotes Neuronal Identity in the Adult Hippocampus.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular neurobiology"
DOI: 10.1007/s12035-020-02222-8
Abstract: Neurogenesis in the dentate gyrus (DG) of the adult hippocampus is actively involved in brain homeostasis. Thus, identification of novel regulators in adult neurogenesis could significantly contribute to new therapies. We have recently unraveled the… read more here.
Keywords: adult; neurogenesis; neuronal identity; nuclear receptor ... See more keywords
Neural development: Relaying control of neuronal identity
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Neuroscience"
DOI: 10.1038/nrn.2016.185
Abstract: The stage-specific regulation of sets of enhancers by the 'programming' transcription factor islet 1 regulates the transcription of effector genes during motor neuron differentiation. read more here.
Keywords: control neuronal; neuronal identity; neural development; relaying control ... See more keywords
LONGO: an R package for interactive gene length dependent analysis for neuronal identity
Sign Up to like & getrecommendations! Published in 2018 at "Bioinformatics"
DOI: 10.1093/bioinformatics/bty243
Abstract: Motivation Reprogramming somatic cells into neurons holds great promise to model neuronal development and disease. The efficiency and success rate of neuronal reprogramming, however, may vary between different conversion platforms and cell types, thereby necessitating… read more here.
Keywords: package; gene; neuronal identity; gene length ... See more keywords
In silico analysis of the transcriptional regulatory logic of neuronal identity specification throughout the C. elegans nervous system
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.64906
Abstract: The generation of the enormous diversity of neuronal cell types in a differentiating nervous system entails the activation of neuron type-specific gene batteries. To examine the regulatory logic that controls the expression of neuron type-specific… read more here.
Keywords: system; neuronal identity; nervous system; regulatory logic ... See more keywords