Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons.
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DOI: 10.1016/j.molcel.2018.10.008
Abstract: Alternative splicing is crucial for diverse cellular, developmental, and pathological processes. However, the full networks of factors that control individual splicing events are not known. Here, we describe a CRISPR-based strategy for the genome-wide elucidation… read more here.
Keywords: genome wide; mechanism; autism; wide crispr ... See more keywords