P85 regulates neuronal migration through affecting neuronal morphology during mouse corticogenesis
Sign Up to like & getrecommendations! Published in 2017 at "Cell and Tissue Research"
DOI: 10.1007/s00441-017-2707-8
Abstract: In mammalian developing embryonic cortex, projection neurons migrate from the ventricular zone to the cortical plate, guided by radial glial cells with a transformation between bipolar and multipolar morphology. Previous studies have demonstrated that the… read more here.
Keywords: morphology mouse; neuronal morphology; p85; neuronal migration ... See more keywords
Sevoflurane Postconditioning Ameliorates Neuronal Migration Disorder Through Reelin/Dab1 and Improves Long-term Cognition in Neonatal Rats After Hypoxic-Ischemic Injury.
Sign Up to like & getrecommendations! Published in 2021 at "Neurotoxicity research"
DOI: 10.1007/s12640-021-00377-3
Abstract: Sevoflurane postconditioning (SPC) has been widely reported to attenuate brain injury after hypoxia-ischemia encephalopathy (HIE) by inhibiting neural necrosis and autophagy. Moreover, recent reports revealed that sevoflurane facilitated hippocampal reconstruction via regulating migration. Yet, it… read more here.
Keywords: reelin dab1; migration disorder; migration; neuronal migration ... See more keywords
A Primate-Specific Isoform of PLEKHG6 Regulates Neurogenesis and Neuronal Migration.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.11.029
Abstract: The mammalian neocortex has undergone remarkable changes through evolution. A consequence of such rapid evolutionary events could be a trade-off that has rendered the brain susceptible to certain neurodevelopmental and neuropsychiatric conditions. We analyzed the… read more here.
Keywords: brain; plekhg6; primate specific; neuronal migration ... See more keywords
Postnatal neuronal migration in health and disease
Sign Up to like & getrecommendations! Published in 2021 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2020.06.001
Abstract: Postnatal neuronal migration modulates neuronal circuit formation and function throughout life and is conserved among species. Pathological conditions activate the generation of neuroblasts in the ventricular-subventricular zone (V-SVZ) and promote their migration towards a lesion.… read more here.
Keywords: postnatal neuronal; migration; health disease; neuronal migration ... See more keywords
Posterior Neocortex-Specific Regulation of Neuronal Migration by CEP85L Identifies Maternal Centriole-Dependent Activation of CDK5
Sign Up to like & getrecommendations! Published in 2020 at "Neuron"
DOI: 10.1016/j.neuron.2020.01.030
Abstract: Genes mutated in human neuronal migration disorders encode tubulin proteins and a variety of tubulin-binding and -regulating proteins, but it is very poorly understood how these proteins function together to coordinate migration. Additionally, the way… read more here.
Keywords: migration; maternal centriole; neuronal migration; activation ... See more keywords
Stigmasterol promotes neuronal migration via reelin signaling in neurosphere migration assays
Sign Up to like & getrecommendations! Published in 2018 at "Nutritional Neuroscience"
DOI: 10.1080/1028415x.2018.1544970
Abstract: Stigmasterol (ST) is a multifunctional phytosterol and is found in diverse food. In our previous transcriptomics study, we found ST upregulated migration-related genes. In the present study, we carried out in vitro neurosphere migration assays… read more here.
Keywords: stigmasterol promotes; migration; neuronal migration; migration assays ... See more keywords
Tubulin diversity and neuronal migration
Sign Up to like & getrecommendations! Published in 2018 at "Cell Cycle"
DOI: 10.1080/15384101.2018.1439822
Abstract: Neuronal migration is a fundamental mechanism that leads immature neuronal precursors to their place of maturation within the central nervous system. This occurs during development and is maintained in specific areas in the adult brain.… read more here.
Keywords: tubulin diversity; migration; neuronal migration; composition ... See more keywords
Human Cytomegalovirus IE1 Impairs Neuronal Migration by Downregulating Connexin 43
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Virology"
DOI: 10.1128/jvi.00313-23
Abstract: Congenital CMV (cCMV) infection causes neurological sequelae in newborns. Recent studies of cCMV pathogenesis in animal models reveal ventriculomegaly and cortical atrophy associated with impaired neural progenitor cell (NPC) proliferation and migration. ABSTRACT Human cytomegalovirus… read more here.
Keywords: neuronal migration; ie1; cx43; infection ... See more keywords
MANF Is Essential for Neurite Extension and Neuronal Migration in the Developing Cortex
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DOI: 10.1523/eneuro.0214-17.2017
Abstract: Visual Abstract Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER) resident protein with neuroprotective effects. Previous studies have shown that MANF expression is altered in the developing rodent cortex in a spatiotemporal manner.… read more here.
Keywords: manf; manf essential; neuronal migration; neurite extension ... See more keywords
Involvement of Netrins and Their Receptors in Neuronal Migration in the Cerebral Cortex
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.590009
Abstract: In mammals, excitatory cortical neurons develop from the proliferative epithelium and progenitor cells in the ventricular zone and subventricular zone, and migrate radially to the cortical plate, whereas inhibitory GABAergic interneurons are born in the… read more here.
Keywords: involvement netrins; netrins receptors; migration; neuronal migration ... See more keywords
Loss of BAF Complex in Developing Cortex Perturbs Radial Neuronal Migration in a WNT Signaling-Dependent Manner
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2021.687581
Abstract: Radial neuronal migration is a key neurodevelopmental event indispensable for proper cortical laminar organization. Cortical neurons mainly use glial fiber guides, cell adhesion dynamics, and cytoskeletal remodeling, among other discrete processes, to radially trek from… read more here.
Keywords: wnt signaling; cortex; migration; neuronal migration ... See more keywords