Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-17521-w
Abstract: Brain organoids are promising tools for disease modeling and drug development. For proper neuronal network formation excitatory and inhibitory neurons as well as glia need to co-develop. Here, we report the directed self-organization of human… read more here.
Keywords: network; gaba polarity; neuronal organoids; polarity switch ... See more keywords
Generation of human otic neuronal organoids using pluripotent stem cells
Sign Up to like & getrecommendations! Published in 2023 at "Cell Proliferation"
DOI: 10.1111/cpr.13434
Abstract: Otic neurons, also known as spiral ganglion neurons (SGNs) in mammalian cochlea, transmit electrical signals from sensory hair cells to cochlear nuclei of the auditory system. SGNs are sensitive to toxic insults, vulnerable to get… read more here.
Keywords: otic neuronal; pluripotent stem; human otic; neuronal organoids ... See more keywords