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   Articles with "neuronal pas" as a keyword



Neuronal PAS domain 1 identifies a major subpopulation of wakefulness-promoting GABAergic neurons in the basal forebrain

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recommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2321410121

Abstract: Significance The basal forebrain (BF) is involved in control of sleep, cortical oscillations, attention, feeding, reward, and olfaction. Here, we characterize a major subset of BF GABAergic neurons which express neuronal PAS domain 1 (Npas1),… read more here.

Keywords: neuronal pas; basal forebrain; major subpopulation; pas domain ... See more keywords

Neuronal PAS domain protein 4 (Npas4) controls neuronal homeostasis in pentylenetetrazole‐induced epilepsy through the induction of Homer1a

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recommendations! Published in 2018 at "Journal of Neurochemistry"

DOI: 10.1111/jnc.14274

Abstract: Neuronal intrinsic homeostatic scaling‐down of excitatory synapse has been implicated in epilepsy pathogenesis to prevent the neuronal circuits from hyperexcitability. Recent findings suggest a role for neuronal PAS domain protein 4 (Npas4), an activity‐dependent neuron‐specific… read more here.

Keywords: pas domain; npas4; neuronal pas; npas4ko mice ... See more keywords

In vitro assessment of Neuronal PAS domain 2 mitigating compounds for scarless wound healing

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recommendations! Published in 2023 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2022.1014763

Abstract: Background The core circadian gene Neuronal PAS domain 2 (NPAS2) is expressed in dermal fibroblasts and has been shown to play a critical role in regulating collagen synthesis during wound healing. We have performed high… read more here.

Keywords: collagen synthesis; neuronal pas; pas domain; wound healing ... See more keywords

Targeting neuronal PAS domain protein 2 and KN motif/ankyrin repeat domains 1: Advances in type 2 diabetes therapy

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recommendations! Published in 2024 at "World Journal of Diabetes"

DOI: 10.4239/wjd.v15.i11.2173

Abstract: This editorial summarizes the latest literature on the roles of neuronal PAS domain protein 2 and KN motif/ankyrin repeat domain 1 in type 2 diabetes (T2D). We highlight their involvement in β-cell dysfunction, explore their… read more here.

Keywords: neuronal pas; protein motif; domain protein; motif ankyrin ... See more keywords