Articles with "neuronal polarization" as a keyword



MTEP impedes the neuronal polarization and the activity of the Akt–NF‐κB pathway in rat hippocampal neurons

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Published in 2017 at "Journal of Neuroscience Research"

DOI: 10.1002/jnr.24002

Abstract: Metabotropic glutamate receptor 5 (mGluR5) is extensively involved in neural survival, differentiation, dendritic morphology, synaptic plasticity, and neural circuit formation. However, little is known about its role in neuronal polarization and axon outgrowth. In this… read more here.

Keywords: hippocampal neurons; axon outgrowth; mglur5; neuronal polarization ... See more keywords
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Axon Regeneration: Antagonistic Signaling Pairs in Neuronal Polarization.

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Published in 2018 at "Trends in molecular medicine"

DOI: 10.1016/j.molmed.2018.05.007

Abstract: Genome-wide screens, proteomics, and candidate-based approaches have identified numerous genes associated with neuronal regeneration following central nervous system (CNS) injury. Despite significant progress, functional recovery remains a challenge, even in model systems. Neuronal function depends… read more here.

Keywords: axon regeneration; neuronal polarization; polarization axon; signaling pairs ... See more keywords
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α-TubK40me3 is required for neuronal polarization and migration by promoting microtubule formation

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Published in 2021 at "Nature Communications"

DOI: 10.1038/s41467-021-24376-2

Abstract: Tri-methylation on lysine 40 of α-tubulin (α-TubK40me3) is a recently identified post-translational modification involved in mitosis and cytokinesis. However, knowledge about α-TubK40me3 in microtubule function and post-mitotic cells remains largely incomplete. Here, we report that… read more here.

Keywords: microtubule; tubk40me3; neuronal polarization; microtubule formation ... See more keywords