Neuronal proteins as targets of 3-hydroxykynurenine: Implications in neurodegenerative diseases.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00265
Abstract: The neurotoxic activity of the tryptophan metabolite 3-hydroxykynurenine (3OHKyn) in neurodegenerative disorders as Parkinson's and Alzheimer's diseases, is related to oxidative stress and 3OHKyn interaction with cellular proteins. The pattern of protein modification induced by… read more here.
Keywords: targets hydroxykynurenine; hydroxykynurenine implications; neurodegenerative diseases; implications neurodegenerative ... See more keywords
Neuronal Proteins as Antigenic Targets in Membranous Nephropathy.
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DOI: 10.1159/000528078
Abstract: CONTEXT The discovery of new target antigens in membranous nephropathy (MN) has revealed new disease phenotypes and, in some cases, has suggested mechanisms of disease shared by two concurrent autoimmune diseases. Subject of Review: Several… read more here.
Keywords: antigenic targets; targets membranous; neuronal proteins; proteins antigenic ... See more keywords
Autoantibodies targeting neuronal proteins as biomarkers for neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2022 at "Theranostics"
DOI: 10.7150/thno.72126
Abstract: Neurodegenerative diseases (NDDs) are associated with the accumulation of a range of misfolded proteins across the central nervous system and related autoimmune responses, including the generation of antibodies and the activation of immune cells. Both… read more here.
Keywords: biomarkers neurodegenerative; autoantibodies targeting; proteins biomarkers; neuronal proteins ... See more keywords