22(R)-hydroxycholesterol for dopaminergic neuronal specification of MSCs and amelioration of Parkinsonian symptoms in rats
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DOI: 10.1038/s41420-020-00351-6
Abstract: Oxysterols play vital roles in the human body, ranging from cell cycle regulation and progression to dopaminergic neurogenesis. While naïve human mesenchymal stem cells (hMSCs) have been explored to have neurogenic effect, there is still… read more here.
Keywords: dopaminergic neuronal; effect; hydroxycholesterol dopaminergic; neuronal specification ... See more keywords
Multiple neural bHLHs ensure the precision of a neuronal specification event in Caenorhabditis elegans
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DOI: 10.1242/bio.058976
Abstract: ABSTRACT Neural bHLH transcription factors play a key role in the early steps of neuronal specification in many animals. We have previously observed that the Achaete-Scute HLH-3, the Olig HLH-16 and their binding partner the… read more here.
Keywords: specification event; caenorhabditis elegans; neuronal specification; specification ... See more keywords