Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Psychiatry"
DOI: 10.1038/s41380-021-01273-0
Abstract: Dopaminergic neurons are critical to movement, mood, addiction, and stress. Current techniques for generating dopaminergic neurons from human induced pluripotent stem cells (hiPSCs) yield heterogenous cell populations with variable purity and inconsistent reproducibility between donors,… read more here.
Keywords: subtype specific; psychiatric disease; dopaminergic neurons; neuronal subtype ... See more keywords
Microglia Don’t Treat All Neurons the Same: The Importance of Neuronal Subtype in Microglia-Neuron Interactions in the Developing Hypothalamus
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.867217
Abstract: Microglia are now well-known as integral regulators of brain development, phagocytosing whole neurons, and pruning weak or excess synapses in order to sculpt and refine immature circuits. However, the importance of neuronal subtype in guiding… read more here.
Keywords: developing hypothalamus; microglia neuron; microglia treat; importance neuronal ... See more keywords