Antibodies to neuronal surface proteins in Tourette Syndrome: Lack of evidence in a European paediatric cohort
Sign Up to like & getrecommendations! Published in 2019 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2019.08.008
Abstract: In Tourette Syndrome (TS) a role for autoantibodies directed against neuronal proteins has long been suspected, but so far results are still inconsistent. The aim of this study was to look for antibodies to specific… read more here.
Keywords: neuronal surface; evidence; antibodies binding; brain ... See more keywords
Epidemiology of neuronal surface antibody-mediated autoimmune encephalitis and antibody-based diagnostics
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2021.577598
Abstract: Epidemiologic data on neuronal surface antibody (NSAb)-associated autoimmune encephalitides (NSAE) are scarce and heterogeneous. We review our 13-year-long biobank-data collection and provide the incidence of NSAE in two Italian provinces (approx. Population of 1,400,000) over… read more here.
Keywords: neuronal surface; antibody; epidemiology; encephalitis ... See more keywords
Efficacy of tacrolimus as long-term immunotherapy for neuronal surface antibody-mediated autoimmune encephalitis
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic Advances in Chronic Disease"
DOI: 10.1177/20406223211063055
Abstract: Aims: We aimed to verify the efficacy and safety of tacrolimus as long-term immunotherapy for the treatment of neuronal surface antibody-mediated autoimmune encephalitis (AE) during the first attack. Methods: In this retrospective observational cohort study,… read more here.
Keywords: tacrolimus; neuronal surface; antibody mediated; surface antibody ... See more keywords
Clinical significance of anti-NMDAR concurrent with glial or neuronal surface antibodies
Sign Up to like & getrecommendations! Published in 2020 at "Neurology"
DOI: 10.1212/wnl.0000000000009239
Abstract: Objective To determine the frequency and significance of concurrent glial (glial-Ab) or neuronal-surface (NS-Ab) antibodies in patients with anti–NMDA receptor (NMDAR) encephalitis. Methods Patients were identified during initial routine screening of a cohort (C1) of… read more here.
Keywords: surface antibodies; anti nmdar; significance; neuronal surface ... See more keywords
Neuronal Surface Autoantibodies in Neuropsychiatric Disorders: Are There Implications for Depression?
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.00752
Abstract: Autoimmune diseases are affecting around 7.6–9.4% of the general population. A number of central nervous system disorders, including encephalitis and severe psychiatric disorders, have been demonstrated to associate with specific neuronal surface autoantibodies (NSAbs). It… read more here.
Keywords: depression; autoantibodies targeting; autoantibodies neuropsychiatric; neuronal surface ... See more keywords
Neuronal surface antigen-specific immunostaining pattern on a rat brain immunohistochemistry in autoimmune encephalitis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1066830
Abstract: A variety of neuronal surface (NS) antibodies (NS-Ab) have been identified in autoimmune encephalitis (AE). Tissue-based assay (TBA) using a rodent brain immunohistochemistry (IHC) is used to screen NS-Ab, while cell-based assay (CBA) to determine… read more here.
Keywords: immunostaining pattern; brain; gfap; reactivity ... See more keywords
Immune-Mediated Cerebellar Ataxia Associated With Neuronal Surface Antibodies
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.813926
Abstract: Background Immune-mediated cerebellar ataxias (IMCAs) are common in paraneoplastic cerebellar degeneration (PCD) but rarely occur in patients with neuronal surface antibodies (NSAbs). Although cerebellar ataxias (CAs) associated with anti-NMDAR and anti-CASPR2 have been reported in… read more here.
Keywords: surface antibodies; neuronal surface; associated cas; anti nsabs ... See more keywords
Autoimmune Encephalitis and Other Neurological Syndromes With Rare Neuronal Surface Antibodies in Children: A Systematic Literature Review
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.866074
Abstract: Neuronal surface antibody syndromes (NSAS) are an expanding group of autoimmune neurological diseases, whose most frequent clinical manifestation is autoimmune encephalitis (AE). Anti-NMDAR, anti-LGI1, and anti-CASPR2 autoimmunity represent the most described forms, while other NSAS… read more here.
Keywords: autoimmune encephalitis; review; autoimmunity; anti ... See more keywords
Activity-dependent Golgi satellite formation in dendrites reshapes the neuronal surface glycoproteome
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DOI: 10.7554/elife.68910
Abstract: Activity-driven changes in the neuronal surface glycoproteome are known to occur with synapse formation, plasticity, and related diseases, but their mechanistic basis and significance are unclear. Here, we observed that N-glycans on surface glycoproteins of… read more here.
Keywords: surface; golgi; activity; neuronal surface ... See more keywords