Articles with "neuronal survival" as a keyword



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Hyperthermia alters neurobehavior by affecting cell proliferation and neuronal survival in young male rats

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Published in 2023 at "International Journal of Developmental Neuroscience"

DOI: 10.1002/jdn.10258

Abstract: Maintenance of body temperature within physiological range is critical for the fetal and neonatal development. Hyperthermia is one of the most frequently encountered pediatric complaints and may cause neurological disorders due to neuronal injury. In… read more here.

Keywords: neuronal survival; cell; hyperthermia; cell proliferation ... See more keywords
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DTYMK is essential for genome integrity and neuronal survival

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Published in 2021 at "Acta Neuropathologica"

DOI: 10.1007/s00401-021-02394-0

Abstract: Nucleotide metabolism is a complex pathway regulating crucial cellular processes such as nucleic acid synthesis, DNA repair and proliferation. This study shows that impairment of the biosynthesis of one of the building blocks of DNA,… read more here.

Keywords: neuronal survival; essential genome; genome integrity; genome ... See more keywords
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Role of Cytosolic Carboxypeptidase 5 in Neuronal Survival and Spermatogenesis

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/srep41428

Abstract: Proteins may undergo a type of posttranslational modification – polyglutamylation, where a glutamate residue is enzymatically linked to the γ-carboxyl group of a glutamate in the primary sequence of proteins and additional glutamates are then… read more here.

Keywords: spermatogenesis; ccp5; neuronal survival; carboxyl ... See more keywords
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Nuclear WRAP53 promotes neuronal survival and functional recovery after stroke

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Published in 2020 at "Science Advances"

DOI: 10.1126/sciadv.abc5702

Abstract: Ischemia-induced WRAP53 nuclear accumulation promotes DNA damage repair resulting in functional recovery after stroke. Failure of neurons to efficiently repair DNA double-strand breaks (DSBs) contributes to cerebral damage after stroke. However, the molecular machinery that… read more here.

Keywords: dna repair; functional recovery; recovery stroke; neuronal survival ... See more keywords
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Corrigendum to “Ambroxol Improves Neuronal Survival and Reduces White Matter Damage through Suppressing Endoplasmic Reticulum Stress in Microglia after Intracerebral Hemorrhage”

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Published in 2020 at "BioMed Research International"

DOI: 10.1155/2020/7941716

Abstract: [This corrects the article DOI: 10.1155/2020/8131286.]. read more here.

Keywords: corrigendum ambroxol; ambroxol improves; reduces white; improves neuronal ... See more keywords
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Stage 1 Registered Report: Effect of deficient phagocytosis on neuronal survival and neurological outcome after temporary middle cerebral artery occlusion (tMCAo)

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Published in 2017 at "F1000Research"

DOI: 10.12688/f1000research.12537.3

Abstract: Stroke is a major cause of death and disability worldwide. In addition to neuronal death resulting directly from energy depletion due to lack of blood supply, inflammation and microglial activation following ischemic brain injury has… read more here.

Keywords: survival neurological; phagocytosis; cerebral artery; middle cerebral ... See more keywords
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Differential Hippocampal Expression of BDNF Isoforms and Their Receptors Under Diverse Configurations of the Serotonergic System in a Mice Model of Increased Neuronal Survival

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Published in 2019 at "Frontiers in Cellular Neuroscience"

DOI: 10.3389/fncel.2019.00384

Abstract: Neurotrophic factors are relevant regulators of the neurogenic process at different levels. In particular, the brain-derived neurotrophic factor, BDNF, is highly expressed in the hippocampus (HC) of rodents and participates in the control of neuronal… read more here.

Keywords: expression; mice; expression bdnf; bdnf isoforms ... See more keywords
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Improved neuron protection following cortical injury in the absence of Semaphorin4B

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Published in 2022 at "Frontiers in Cellular Neuroscience"

DOI: 10.3389/fncel.2022.1076281

Abstract: Injury to the central nervous system induces neuronal cell death and astrogliosis, an astrocyte-mediated response that has both a beneficial and detrimental impact on surrounding neuronal cells. The circumstance however, in which astrogliosis improves neuronal… read more here.

Keywords: neuronal survival; knockout mice; semaphorin4b; injury ... See more keywords
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The Role of MEF2 Transcription Factor Family in Neuronal Survival and Degeneration

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24043120

Abstract: The family of myocyte enhancer factor 2 (MEF2) transcription factors comprises four highly conserved members that play an important role in the nervous system. They appear in precisely defined time frames in the developing brain… read more here.

Keywords: neuronal survival; transcription; factor; transcription factor ... See more keywords
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Exploring the role of interleukin-27 as a regulator of neuronal survival in central nervous system diseases

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Published in 2022 at "Neural Regeneration Research"

DOI: 10.4103/1673-5374.336134

Abstract: Interleukin-27 is a pleiotropic cytokine that is involved in tissue responses to infection, cell stress, neuronal disease, and tumors. Recent studies in various tissues indicate that interleukin-27 has complex activating and inhibitory properties in innate… read more here.

Keywords: neuronal survival; central nervous; system diseases; nervous system ... See more keywords