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Published in 2023 at "International Journal of Developmental Neuroscience"
DOI: 10.1002/jdn.10258
Abstract: Maintenance of body temperature within physiological range is critical for the fetal and neonatal development. Hyperthermia is one of the most frequently encountered pediatric complaints and may cause neurological disorders due to neuronal injury. In…
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Keywords:
neuronal survival;
cell;
hyperthermia;
cell proliferation ... See more keywords
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Published in 2021 at "Acta Neuropathologica"
DOI: 10.1007/s00401-021-02394-0
Abstract: Nucleotide metabolism is a complex pathway regulating crucial cellular processes such as nucleic acid synthesis, DNA repair and proliferation. This study shows that impairment of the biosynthesis of one of the building blocks of DNA,…
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Keywords:
neuronal survival;
essential genome;
genome integrity;
genome ... See more keywords
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Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep41428
Abstract: Proteins may undergo a type of posttranslational modification – polyglutamylation, where a glutamate residue is enzymatically linked to the γ-carboxyl group of a glutamate in the primary sequence of proteins and additional glutamates are then…
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Keywords:
spermatogenesis;
ccp5;
neuronal survival;
carboxyl ... See more keywords
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Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.abc5702
Abstract: Ischemia-induced WRAP53 nuclear accumulation promotes DNA damage repair resulting in functional recovery after stroke. Failure of neurons to efficiently repair DNA double-strand breaks (DSBs) contributes to cerebral damage after stroke. However, the molecular machinery that…
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Keywords:
dna repair;
functional recovery;
recovery stroke;
neuronal survival ... See more keywords
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Published in 2020 at "BioMed Research International"
DOI: 10.1155/2020/7941716
Abstract: [This corrects the article DOI: 10.1155/2020/8131286.].
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Keywords:
corrigendum ambroxol;
ambroxol improves;
reduces white;
improves neuronal ... See more keywords
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Published in 2017 at "F1000Research"
DOI: 10.12688/f1000research.12537.3
Abstract: Stroke is a major cause of death and disability worldwide. In addition to neuronal death resulting directly from energy depletion due to lack of blood supply, inflammation and microglial activation following ischemic brain injury has…
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Keywords:
survival neurological;
phagocytosis;
cerebral artery;
middle cerebral ... See more keywords
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Published in 2019 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2019.00384
Abstract: Neurotrophic factors are relevant regulators of the neurogenic process at different levels. In particular, the brain-derived neurotrophic factor, BDNF, is highly expressed in the hippocampus (HC) of rodents and participates in the control of neuronal…
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Keywords:
expression;
mice;
expression bdnf;
bdnf isoforms ... See more keywords
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Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.1076281
Abstract: Injury to the central nervous system induces neuronal cell death and astrogliosis, an astrocyte-mediated response that has both a beneficial and detrimental impact on surrounding neuronal cells. The circumstance however, in which astrogliosis improves neuronal…
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Keywords:
neuronal survival;
knockout mice;
semaphorin4b;
injury ... See more keywords
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Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043120
Abstract: The family of myocyte enhancer factor 2 (MEF2) transcription factors comprises four highly conserved members that play an important role in the nervous system. They appear in precisely defined time frames in the developing brain…
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Keywords:
neuronal survival;
transcription;
factor;
transcription factor ... See more keywords
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Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.336134
Abstract: Interleukin-27 is a pleiotropic cytokine that is involved in tissue responses to infection, cell stress, neuronal disease, and tumors. Recent studies in various tissues indicate that interleukin-27 has complex activating and inhibitory properties in innate…
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Keywords:
neuronal survival;
central nervous;
system diseases;
nervous system ... See more keywords