Glucocerebrosidase Activity Modulates Neuronal Susceptibility to Pathological α-Synuclein Insult
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DOI: 10.1016/j.neuron.2019.12.004
Abstract: Mutations in the GBA1 gene are the most common genetic risk factor for Parkinson's disease (PD) and dementia with Lewy bodies (DLB). GBA1 encodes the lysosomal lipid hydrolase glucocerebrosidase (GCase), and its activity has been… read more here.
Keywords: synuclein; activity modulates; activity; neuronal susceptibility ... See more keywords