Development of a fully human assay combining NGN2-inducible neurons co-cultured with iPSC-derived astrocytes amenable for electrophysiological studies.
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DOI: 10.1016/j.scr.2021.102386
Abstract: Neurogenin 2 encodes a neural-specific transcription factor (NGN2) able to drive neuronal fate on somatic and stem cells. NGN2 is expressed in neural progenitors within the developing central and peripheral nervous systems. Overexpression of NGN2… read more here.
Keywords: neurons cultured; development fully; fully human; stem cells ... See more keywords