Reduced Dynamin-I levels in neurons lacking MUNC18-1.
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DOI: 10.1242/jcs.260132
Abstract: MUNC18-1/Syntaxin binding protein-1 (Stxbp1), binds Syntaxin-1. Together, these proteins regulate synaptic vesicle exocytosis and have a separate role in neuronal viability. In MUNC18-1/Stxbp1 null mutant neurons, Syntaxin-1 protein levels are 70% reduced. Here, we show… read more here.
Keywords: null mutant; stxbp1 null; munc18; neurons lacking ... See more keywords