The impact of antidiabetic treatment on human hypothalamic infundibular neurons and microglia
Sign Up to like & getrecommendations! Published in 2020 at "JCI Insight"
DOI: 10.1172/jci.insight.133868
Abstract: Animal studies indicate that hypothalamic dysfunction plays a major role in type 2 diabetes mellitus (T2DM) development, and that insulin resistance and inflammation are important mechanisms involved in this disorder. However, it remains unclear how… read more here.
Keywords: neurons microglia; npy neurons; impact antidiabetic; antidiabetic treatment ... See more keywords
The Duration of Stress Determines Sex Specificities in the Vulnerability to Depression and in the Morphologic Remodeling of Neurons and Microglia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2022.834821
Abstract: Stress exposure has been shown to induce a variety of molecular and functional alterations associated with anxiety and depression. Some studies suggest that microglia, the immune cells of the brain, play a significant role in… read more here.
Keywords: stress; term ucms; depression; neurons microglia ... See more keywords
Neurons and Microglia; A Sickly-Sweet Duo in Diabetic Pain Neuropathy
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2019.00025
Abstract: Diabetes is a common condition characterized by persistent hyperglycemia. High blood sugar primarily affects cells that have a limited capacity to regulate their glucose intake. These cells include capillary endothelial cells in the retina, mesangial… read more here.
Keywords: sickly sweet; neurons microglia; pain neuropathy; microglia sickly ... See more keywords