Ganoderma lucidum extract ameliorates MPTP-induced parkinsonism and protects dopaminergic neurons from oxidative stress via regulating mitochondrial function, autophagy, and apoptosis
Sign Up to like & getrecommendations! Published in 2018 at "Acta Pharmacologica Sinica"
DOI: 10.1038/s41401-018-0077-8
Abstract: Neuroprotection targeting mitochondrial dysfunction has been proposed as an important therapeutic strategy for Parkinson’s disease. Ganoderma lucidum (GL) has emerged as a novel agent that protects neurons from oxidative stress. However, the detailed mechanisms underlying… read more here.
Keywords: gle; via regulating; neurons oxidative; parkinsonism ... See more keywords
Procyanidin B2 Protects Neurons from Oxidative, Nitrosative, and Excitotoxic Stress
Sign Up to like & getrecommendations! Published in 2017 at "Antioxidants"
DOI: 10.3390/antiox6040077
Abstract: The aberrant generation of oxygen and nitrogen free radicals can cause severe damage to key cellular components, resulting in cell apoptosis. Similarly, excitotoxicity leads to protease activation and mitochondrial dysfunction, which subsequently causes cell death.… read more here.
Keywords: pb2; procyanidin protects; apoptosis; neurons oxidative ... See more keywords