Herbal medicinal products or preparations for neuropathic pain.
Sign Up to like & getrecommendations! Published in 2017 at "Cochrane Database of Systematic Reviews"
DOI: 10.1002/14651858.cd010528.pub3
Abstract: BACKGROUND Neuropathic pain is a consequence of damage to the central nervous system (CNS), for example, cerebrovascular accident, multiple sclerosis or spinal cord injury, or peripheral nervous system (PNS), for example, painful diabetic neuropathy (PDN),… read more here.
Keywords: medicinal products; evidence; effect; herbal medicinal ... See more keywords
Antidepressant drugs for neuropathic pain - an overview of Cochrane reviews
Sign Up to like & getrecommendations! Published in 2017 at "Cochrane Database of Systematic Reviews"
DOI: 10.1002/14651858.cd011606.pub2
Abstract: Reason for withdrawal from publication At January 2017, this protocol has been withdrawn as it will now form part of a separate non-Cochrane overview on drugs for neuropathic pain. read more here.
Keywords: drugs neuropathic; overview; neuropathic pain; reviews antidepressant ... See more keywords
Superoxide Dismutase-Loaded Porous Polymersomes as Highly Efficient Antioxidants for Treating Neuropathic Pain.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201700500
Abstract: A highly efficient antioxidant is developed by encapsulating superoxide dismutase (SOD) within the aqueous interior of porous polymersomes. The porous polymersomes provide a permeable membrane that allows free superoxide radicals to pass into the aqueous… read more here.
Keywords: neuropathic pain; superoxide dismutase; highly efficient; porous polymersomes ... See more keywords
N6‐Methyladenosine Demethylase FTO Contributes to Neuropathic Pain by Stabilizing G9a Expression in Primary Sensory Neurons
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Science"
DOI: 10.1002/advs.201902402
Abstract: Abstract Nerve injury‐induced change in gene expression in primary sensory neurons of dorsal root ganglion (DRG) is critical for neuropathic pain genesis. N6‐methyladenosine (m6A) modification of RNA represents an additional layer of gene regulation. Here,… read more here.
Keywords: sensory neurons; neuropathic pain; nerve injury; primary sensory ... See more keywords
Neuronal C‐Reactive Protein/FcγRI Positive Feedback Proinflammatory Signaling Contributes to Nerve Injury Induced Neuropathic Pain
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202205397
Abstract: Neuropathic pain is difficult to treat in clinical practice, and the underlying mechanisms are insufficiently elucidated. Previous studies have demonstrated that the neuronal Fc‐gamma‐receptor type I (FcγRI) of the dorsal root ganglion (DRG) mediates antigen‐specific… read more here.
Keywords: nerve injury; neuropathic pain; pain; reactive protein ... See more keywords
The efficacy and safety of botulinum toxin type A in treatment of trigeminal neuralgia and peripheral neuropathic pain: A meta‐analysis of randomized controlled trials
Sign Up to like & getrecommendations! Published in 2019 at "Brain and Behavior"
DOI: 10.1002/brb3.1409
Abstract: Although recent studies have shown that botulinum toxin‐A (BTX‐A) has a good analgesic effect on trigeminal neuralgia (TN) and peripheral neuropathic pain (PNP), the quality of evidence is low due to limited data. This meta‐analysis… read more here.
Keywords: peripheral neuropathic; neuralgia peripheral; trigeminal neuralgia; neuropathic pain ... See more keywords
Involvement of the BDNF–TrkB–KCC2 pathway in neuropathic pain after brachial plexus avulsion
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2464
Abstract: Brachial plexus avulsion significantly increased brain‐derived neurotrophic factor (BDNF) release in the spinal cord. Here we investigated the involvement of the BDNF–TrkB–KCC2 pathway in neuropathic pain caused by BPA injury. We hypothesized that activation of… read more here.
Keywords: brachial plexus; bdnf trkb; neuropathic pain; bdnf ... See more keywords
The core of maintaining neuropathic pain: Crosstalk between glial cells and neurons (neural cell crosstalk at spinal cord)
Sign Up to like & getrecommendations! Published in 2023 at "Brain and Behavior"
DOI: 10.1002/brb3.2868
Abstract: Neuropathic pain (NP) caused by the injury or dysfunction of the nervous system is a chronic pain state accompanied by hyperalgesia, and the available clinical treatment is relatively scarce. Hyperalgesia mediated by pro‐inflammatory factors and… read more here.
Keywords: maintaining neuropathic; pain crosstalk; core maintaining; crosstalk glial ... See more keywords
BDNF as a biomarker for neuropathic pain: Consideration of mechanisms of action and associated measurement challenges
Sign Up to like & getrecommendations! Published in 2023 at "Brain and Behavior"
DOI: 10.1002/brb3.2903
Abstract: The primary objective of this paper is to (1) provide a summary of human studies that have used brain derived neurotrophic factor (BDNF) as a biomarker, (2) review animal studies that help to elucidate the… read more here.
Keywords: measurement; neuropathic pain; bdnf biomarker;
Evaluation of chiral N,N-dimethyl-sphingosine for the interaction between nerve growth factor and tropomyosin receptor kinase A.
Sign Up to like & getrecommendations! Published in 2022 at "Chirality"
DOI: 10.1002/chir.23433
Abstract: Neuropathic pain is an unbearable condition caused by nervous system damage. As distinct acute pain, neuropathic pain is chronic, and it severely influences quality of life. N,N-Dimethyl-d-erythro-sphingosine (DMS), a neuropathic pain inducer, is metabolited de… read more here.
Keywords: dimethyl; sphingosine; nerve; factor ... See more keywords
Whole‐body reversible neuropathic pain associated with right parieto‐temporal operculum single inflammatory lesion in a patient with multiple sclerosis: A case report
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pain"
DOI: 10.1002/ejp.1464
Abstract: The posterior insula and the medial parietal operculum (PIMO) are part of the pain network. Pain can be induced by direct stimulation of the PIMO, but the clinical consequence of lesions in this brain area… read more here.
Keywords: reversible neuropathic; body reversible; pain; neuropathic pain ... See more keywords